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Thespleenstoresandpurifieserythrocytes,metabolizeshemoglobin,andrecyclesiron.Thespleenalsoprovidesacriticalfunctionfortheimmunesystembymountingaprimaryimmuneresponsetoantigensinthebloodandsynthesizingantibodies[1].SplenocytesaremononuclearcellsderivedfromthespleenandincludeT-lymphocytes,B-lymphocytes,NK-cells,andNKTcells.Primaryratsplenocytes(RS)canbeusedtoisolateCD4+T-cells,CD8+T-cells,andCD45R+Bcells.
RSfromScienCellResearchLaboratoriesareisolatedfromnormaladultCD®IGSratspleen.RSaredepletedofsplenicmacrophages,cryopreserveddirectlyafterisolation,anddeliveredfrozen.Eachvialcontainsatleast10millioncellsin1mlvolume.RSarequalitycontroltestedforviABIlity.RSarenegativeformycoplasma,bacteria,yeast,andfungi.RScanbemaintainedforalimitedperiodoftimeincultureusingtheconditionsprovidedbyScienCellResearchLaboratoriesandarenotintendedforlong-termculture.
Specifications:
CatalogNo. | R5540 |
CountryofManufacture | UnitedStates |
ProductCode | RS |
Size/Quantity | 10millioncellsin1mlvolume |
ProductUse | RSareforresearchuseonly.Theyarenotapprovedforhumanoranimaluse,orforapplicationininvitrodiagnosticprocedures. |
Storage | Uponreceiving,directlyandimmediatelytransferthecellsfromdryicetoliquidnitrogenandkeepthecellsinliquidnitrogenuntiltheyareneededforexperiments. |
ShippingInfo | Dryice. |
References | [1]MebiusR,KraalG.(2005)"Structureandfunctionofthespleen."NatRevImmunol5(8):606-616. |