Description:

Description:Dipeptidylpeptidase-4(DPP4),alsoknownasadenosinedeaminasecomplexingprotein2orCD26(clusterofdifferentiation26)isaproteinthat,inhumans,isencodedbytheDPP4gene.ThesubstratesofCD26/DPP4areproline(oralanine)containingpeptidesandincludegrowthfactors,chemokines,neuropeptides,andvasoactivepeptides.DPP4playsamajorroleinglucosemetabolism.ItisresponsIBLeforthedegradationofincretinssuchasGLP-1andhenceitsinhibitionbydrugssuchasSitagliptinhavebeenusedfortreatmentofdiabetesmellitustype2.DPP4alsoappearstoworkasasuppressorinthedevelopmentofcancerandtumors.InGenWay"sDPP4ActivityAssayKit,DPP4cleavesasubstratetoreleaseaquenchedfluorescentgroup,AMC(7-Amino-4-MethylCoumarin),(Ex/Em=360/460nm).Thisassayisrapid,simple,sensitive,andreliable,aswellas,suitableforhighthroughputactivityscreeningofDPP4.ThiskitdetectsDPP4activityaslowas3µUperwell.
Summary:
-Detectionmethod-Fluorescence(Ex/Em360/460nm)
-Sampletype-CellandTissueculturelysatess,plasma,serum,otherBIOLOGicalfluids,cellculturemediumetc.
-Speciesreactivity-Mammalian
-Applications-ThiskitdetectsDPP4activityaslowas3µUperwell.
Kitcomponents:
-DPP4AssayBuffer
-DPP4Substrate(H-Gly-Pro-AMC)
-DPP4PositiveControl
-AMCStandard(10µM)
-DPP4Inhibitor(Sitagliptin)
FeaturesandBenefits:
-Simpleprocedure;takes~40minutes
-Fastandconvenient
-Sensitive,reliableHTSassay
ShippingConditions:Gelpack

AdditionalInformation:

GenWay公司是为了探索和开发人类蛋白组而成立的。公司的总任务就是用基因特异性抗体來筛选和鉴定新蛋白、其功能及其编码基因，旨在成为以抗体介导的蛋白组研发的领域先锋。基因纬公司已成功地发展出一套有自己知识产权的、新穎、高效、低耗、高筛选通量的鉴定方法――抗体介导的蛋白和基因鉴定。公司提供大量的高质量的蛋白和相应的鸡抗体产品，是蛋白质组学研究的重要工具和有力助手。GenWay Biotech的主要产品包括：ProteinsAntibodiesELISA KitsSecondary AntibodiesReagentsPeptidesMolecular Biology ProductsActive ProteinsEnzymatic AssaysPCR Kits

Name	DPP4ActivityAssayKit
RelatedProductNames	DPP4assay
Format	AssayKit
Storage	-20C
IntendedUse	ResearchUseOnly