ASPP1 (Apoptosis-stimulating of p53 protein 1, Protein phosphatase 1 regulatory subunit 13B, PPP1R13B) plays a central role in regulating apoptosis via its interaction with p53. ASPP1 acts on p53 by enhancing the DNA binding and transactivation function of p53 on the promoters of proapoptotic genes in vivo. The expression of ASPP1 is frequently downregulated in human breast carcinomas expressing wild-type p53 but not mutant p53. Abbiotec为科学界提供定制抗体生产服务，以加速从生物学到Discovery ™ 的项目  。当尚未获得针对所选抗原的抗体时，就该开发定制项目了。Abbiotec的经验丰富的员工以与开发Abbiotec目录抗体产品相同的思维方式和工具来处理定制项目：我们需要在所选应用中能特异性检测抗原的抗体。