The DetectX^® Dehydroepiandrosterone sulfate (DHEA-S) Immunoassay Kit uses a specifically generated antibody to measure DHEA-S in serum, plasma, urine, and saliva samples. The kit will also measure DHEA-S present in fecal extracts and tissue culture media samples.  Standards or diluted samples are pipetted into a clear microtiter plate coated with an antibody to capture sheep antibodies. A DHEA-S-peroxidase conjugate is added to the standards and samples in the wells. The binding reaction is initiated by the addition of a polyclonal antibody to DHEA-S to each well. After a 2 hour incubation the plate is washed and substrate is added. The substrate reacts with the bound DHEA-S-peroxidase conjugate. The intensity of the generated color is detected in a microtiter plate reader at 450nm.

DHEA-S is primarily produced by the adrenal glands and it is useful as a marker for adrenal function. Adrenal tumors, cancers, and hyperplasia can lead to the overproduction of DHEA-S. High DHEA-S levels can lead to amenorrhea and visible symptoms of virilization. These changes vary in severity and may include: a deeper voice, hirsutism, male pattern baldness, muscularity, acne and enlargement of the Adam’s apple. Women with polycystic ovary syndrome tend to have elevated levels of DHEA-S. Excess levels of DHEA-S in children can cause precocious puberty in boys; and ambiguous external genitalia, excess body hair, and abnormal menstrual periods in girls.

自1982年以来，Arbor Assays的创始人和顶尖科学家一直在研究和开发高质量的检测试剂盒。我们从小就生产FDA管制的用于人类疾病检测的体外诊断产品。1991年，当我们开始为生命科学市场生产产品时，我们意识到灵敏度，速度，便利性，质量和服务与这些产品无关。我们为您更改了。2017年1月1日，Arbor Assays通过永久员工福利信托（EBT）成为全球第一家员工拥有的生命科学公司。作为EBT，董事会确保公司为客户和员工的利益而保持独立。对于客户而言，员工拥有权意味着可以依靠公司不断进行试验，创新和提供高质量的产品。对于员工而言，所有权意味着提高工作安全性和职业满意度，而不必担心Arbor Assays将被出售给更大的开发公司。