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This gene is highly conserved during evolution and it plays a key role in the regulation of cell division. The encoded protein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known. [provided by RefSeq].
Titration of the CDC25C antibody may be required due to differences in protocols and secondary/substrate sensitivity.
This CDC25C antibody was produced from a mouse immunized with CDC25C recombinant protein.
Aliquot the CDC25C antibody and store frozen at -20oC or colder.Avoid repeated freeze-thaw cycles.
