NSJ Bio/OCT-2 Antibody / POU2F2 [clone OCT2/2137] (V3913)/100 ug/V3913-100UG

价格
¥9980.00
货号:V3913-100UG
浏览量:17
品牌:NSJ Bio
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商品描述
Description

Oct-2 is a transcription factor of the POU homeo-domain family that binds to the Ig gene octamer sites, regulating B-cell-specific genes. Oct-2 expression can be used as a marker of B-cell lineage and differentiation. Germinal center B-cells, mantle B-cells, monocytoid B-cells, and plasma cells show high level expression of Oct-2. Additionally, mantle cell lymphoma, follicular lymphoma, marginal zone lymphoma, plasmacytoma, Burkitt lymphoma, diffuse large cell lymphoma, diffuse large B-cell lymphoma, Hodgkin lymphoma display increased expression of Oct-2. Several studies of Oct-2 expression have shown a low level expression in pre-B, T-cell, myelomonocytic, and epithelial cell lines, whereas all mature B-cell lines have high levels of expression. In spite of scanty evidence for Oct-2 expression in T cells, it is believed that this factor participates in transcriptional regulation during T-cell activation.

Application Notes

Optimal dilution of the OCT-2 antibody should be determined by the researcher.

Immunogen

A portion of amino acids 112-297 from the human protein was used as the immunogen for the OCT-2 antibody.

Storage

Store the OCT-2 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

NSJBio F53723说明书   ABO Antibody [clone 593CT3.2.2] (F53723) F53723-0.1ML In ascites with 0.09% sodium azide 0.1 ml 299       可用性 1-3个工作日 物种反应性 人的 格式 腹水 克隆 单克隆(小鼠来源) 同型 小鼠IgM 克隆名称 593CT3.2.2 纯度 腹水 UniProt的 P16442 应用 蛋白质印迹:1:200-1:6400 限制 该ABO抗体仅供研究使用。   描述 该基因编码与发现的血型系统ABO相关的蛋白质。个体中存在哪个等位基因决定了血型。'O'血型由蛋白质N-末端附近的鸟嘌呤-258的缺失引起,其导致几乎完全不同的蛋白质的移码和翻译。具有A,B和AB等位基因的个体表达将H抗原转化为A或B抗原的糖基转移酶活性。已发现该基因的其他次要等位基因。 应用笔记 由于方案和二级/底物灵敏度的差异,可能需要滴定ABO抗体。 免疫原 来自人蛋白质的氨基酸41-68的一部分用作该ABO抗体的免疫原。 存储 将ABO抗体等分,并在-20℃或更低温度下冷冻保存。避免反复冻融循环。