OVERVIEW:

Synonyms	Monoclonal TYRO3 antibody, Anti-TYRO3 antibody, TYRO 3 antibody, Tyrosine-protein kinase antibody, TYRO-3 antibody, BYK antibody, Sky antibody, TYRO3, TYRO-3, TYRO 3 antibody, TYRO-3 antibody, Dtk antibody, Brt antibody, TYRO 3
Cross Reactivity	Human
Applications	ELISA, IF, WB
Immunogen	TYRO3 antibody was raised in Mouse using a purified recombinant fragment of TYRO3 expressed in E. coli as the immunogen.

SPECIFICATIONS:

Host	Mouse
Clone	1C10E8, 9A3F2
Isotype	IgG1
Form & Buffer	Supplied as a liquid in ascitic fluid containing 0.03% sodium azide.
Concentration	1.0 mg/ml

STORAGE & SAFETY:

Storage	Store at 4 deg C for short term storage. Store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

Usage Assay Information:

Usage Recommendations	ELISA: 1:10,000, IF: 1:200-1:1000, WB: 1:500-1:2000

GENERAL INFORMATION:

Biological Significance

TYRO3 belongs to the Tyr protein kinase family (AXL/UFO subfamily). The UFO family of receptor tyrosine kinases is comprised of subfamily members Rse(also referred to as Tyro3 or Sky) and UFO (also called Tyro7 or Axl). Protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation.

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