OVERVIEW:

Synonyms	Monoclonal VZV (nucleocapsid) antibody, Anti-VZV (nucleocapsid) antibody, VZV (nucleocapsid) antibody, Anti VZV (nucleocapsid) antibody, Varicella Zoster Virus nucleocapsid antibody, Varicella Zoster Virus nucleocapsid antibody
Specificity	Varicella zoster virus
Cross Reactivity	To be determined by end-user
Applications	IF, IP
Immunogen	VZV (nucleocapsid) antibody was raised in mouse using varicella zoster virus HZ strain as the immunogen.

SPECIFICATIONS:

Host	Mouse
Clone	M8110232
Isotype	IgG1
Form & Buffer	Supplied as a liquid with 0.1% NaN3.
Concentration	1.0 mg/ml

STORAGE & SAFETY:

Storage	Aliquot and store at -20 deg C. Avoid repeated Freeze/Thaw cycles
Biohazard Information	This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling.

Usage Assay Information:

Usage Recommendations	Optimal conditions to be determined by end user

GENERAL INFORMATION:

Biological Significance

Varicella-Zoster Virus (VZV) is the etiologic agent of two clinical diseases: Chickenpox (Varicella) and Shingles (Zoster). Chickenpox is an acute generalized disease with the sudden onset of fever and vesicular eruptions of the skin and mucous membranes. After an attack of chickenpox, the Varicella-Zoster virus lies dormant in the nerve tissue with the possibility of reactivation in the form of shingles, which may be manifest as an outbreak of a rash or blisters on the skin. VSV possess a lipid envelope which encloses the nucleocapsid of 162 capsomeres arranged in an icosahedral form.

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