OVERVIEW:

Synonyms	Monoclonal RAC1 antibody, Anti-RAC1 antibody, RA-1c antibody, RA 1c antibody, RA-1c, RA 1c, RAC1, RA-1c antibody, RA 1c antibody
Specificity	Human
Cross Reactivity	Mouse, rat
Applications	IHC, IP, WB
Immunogen	RAC1 antibody was raised in mouse using recombinant protein containing the full length human rac1 as the immunogen.

SPECIFICATIONS:

Host	Mouse
Clone	23A8
Isotype	IgG2b
Method of Purification	RAC1 antibody was purified by Protein G affinity chromatography.
Form & Buffer	0.1M tris-glycine, pH 7.4, with 0.15M NaCl and 0.05% NaN3.
Concentration	1.0 mg/ml

STORAGE & SAFETY:

Storage	Aliquot and store at -20 deg C. Avoid repeated Freeze/Thaw cycles
Biohazard Information	This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling.

Usage Assay Information:

Usage Recommendations	Optimal conditions to be determined by end user

GENERAL INFORMATION:

Biological Significance	Rac1 is a member of a RhoGTPase subfamily (Rac1-Rac4) that transduces extracellular signals from G-coupled protein receptors (GPCR), integrins and growth factor receptors to effector molecules that modulate multiple signaling pathways. While Rac1 supports the activation of MAPkinase pathways and gene activation, it?s most important functions include the regulation of cytoskeletal structures.

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