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联系方式
公司地址
苏州工业园区生物纳米园A4#216
联系电话
4000-520-616 / 18915418616
传真号码
0512-67156496
电子邮箱
info@ebiomall.com
公司网址
https://www.ebiomall.com
商品描述
| ProductDetails | |
|---|---|
| Synonyms | CCS;SuperoxideDismutaseCopperChaperone;CopperChaperoneforSuperoxideDismutase |
| ProductType | Kit |
| Properties | |
| ApplicationSet | CompoundScreening |
| Crossreactivity | Human |
| Quantity | 10x96wells |
| Sensitivity | 20pg/ml |
| AssayType | Sandwich |
| OtherProductData | ClickhereforOriginalManufacturerProductDatasheet Ourproductdescriptionmaydifferslightlyfromtheoriginalmanufacturersproductdatasheet. |
| Declaration | ManufacturedbyAbFrontier |
| ShippingandHandling | |
| Shipping | BLUEICE |
| ShortTermStorage | +4°C |
| LongTermStorage | +4°C |
| HandlingAdvice | Anyunusedreconstitutedstandardshouldbediscardedorfrozenat-80℃. Standardcanbefrozenandthawedonetimeonlywithoutlossofimmunoreactivity. |
| Documents | |
| Manual |  DownloadPDF |
| MSDS | No |
| ProductSpecificationSheet | |
| Datasheet | DownloadPDF |
Superoxidedismutase(SOD)isanantioxidantenzymeinvolvedinthedefensesystemagainstreactiveoxygenspecies(ROS).SODcatalyzesthedismutationreactionofsuperoxiderADIcalanion(O2-)tohydrogenperoxide,whichisthencatalyzedtoinnocuousO2andH2Obyglutathioneperoxidaseandcatalase.SeveralclassesofSODhavebeenidentified.Theseincludeintracellularcopper,zincSOD(Cu,Zn-SOD/SOD-1),mitochondrialmanganeseSOD(Mn-SOD/SOD-2)andextracellularCu,Zn-SOD(EC-SOD/SOD-3)(1).SOD-1isfoundinalleukaryoticspeciesasahomodimeric32-kDaenzymecontainingoneeachofCuandZnionpersubunit(2).Themanganesecontaining80-kDatetramericenzymeSOD2,islocatedinthemitochondrialmatrixincloseproximitytoaprimaryendogenoussourceofsuperoxide,themitochondrialrespiratorychain(3).SOD-3isaheparin-bindingmultimerofdisulfide-linkeddimers,primarilyexpressedinhumanlungs,vesselwallsandairways(4).SOD-4isacopperchaperoneforsuperoxidedismutase(CCS),whichspecificallydeliversCutocopper/zincsuperoxidedismutase.CCSmayactivatecopper/zincsuperoxidedismutasethroughdirectinsertionoftheCucofactor.
