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苏州工业园区生物纳米园A4#216
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4000-520-616 / 18915418616
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0512-67156496
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商品描述
Overview:
| ProductName | Dovitinib |
| Description | FGFR3inhibitor |
| Purity | >98% |
| CASNo. | 405169-16-6 |
| MolecularFormula | C21H21FN6O |
| MolecularWeight | 392.4 |
Properties
| StorageTemperature | -20ºC |
| ShippingTemperature | ShippedAmbient |
| ProductType | Inhibitor |
| Solubility | SolubleinDMSO |
| Source | Synthetic |
| Appearance | Crystallinesolid |
| SMILES | CN1CCN(CC1)C2=CC3=C(C=C2)N=C(N3)C4=C(C5=C(C=CC=C5F)NC4=O)N |
| InChI | InChI=1S/C21H21FN6O/c1-27-7-9-28(10-8-27)12-5-6-14-16(11-12)25-20(24-14)18-19(23)17-13(22)3-2-4-15(17)26-21(18)29/h2-6,11,24-25H,7-10,23H2,1H3/b20-18- |
| InChIKey | KCOYQXZDFIIGCY-ZZEZOPTASA-N |
| SafetyPhrases | Classification:SkinCorrosion/Irritation,Category2SeriousEyeDamage/EyeIrritation,Category2TargetOrganSystemicToxicity(singleexposure),Category3SafetyPhrases:S22-Donotbreathedust.S24/25-Avoidcontactwithskinandeyes.S36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotection.Hazardstatements:H315:Causesskinirritation.H319:Causesseriouseyeirritation.H335:Maycauserespiratoryirritation.Precautionarystatements:P302+352:IFONSKIN:Washwithplentyofsoapandwater.P332+313:Ifskinirritationoccurs,getmedicaladvice/attention.P305+351+338:IFINEYES:Rinsecautiouslywithwaterforseveralminutes.Removecontactlenses,ifpresentandeasytodo.Continuerinsing.P337+313:Ifeyeirritationpersists,getmedicaladvice/attention.P304+340:IFINHALED:Removevictimtofreshairandkeepatrestinapositioncomfortableforbreathing.P312:Calla{POISONCENTER/doctor/...}ifyoufeelunwell. |
| CiteThisProduct | Dovitinib(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-500) |
BIOLOGicalDescription
| AlternativeNames | 4-amino-5-fluoro-3-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-2(1H)-quinolinone |
| ResearchAreas | CellSignaling |
| PubChemID | 9886808 |
| ScientificBackground | DovitinibisapotentgrowthfactorreceptorkinaseinhibitorwitheffectsagainstFLT-3,c-KIT,VEGFR,PDGFRßandCSF-1R. |
| References | 1.KonecnyG.E.,etal.(2013)Mol.CancerTher.12(5):632–642. |
ProductImages
ChemicalstructureofDovitinib(SIH-500),aFGFR3inhibitor.CAS#:405169-16-6.MolecularFormula:C21H21FN6O.MolecularWeight:392.4g/mol.
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