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productdatasheet
CatalogNo.:18711
Size:100ugIgGinPBS,pH7.4,purifiedbyimmunoaffinitychromatography.
Antigen:Peptidecorrespondingtoaa277-293ofhumanDC-SIGN.
HostSpecies:Rabbit
StABIlizers:None
Preservatives:0.02%sodiumazide
ThisantibodyrecognizeshumanDC-SIGN,adendriticcellreceptorthatcancaptureandtransportHIVfrommucosalareastoremotelymphnodeswhereHIVisthentransferredtoCD4+Tlymphocytes.MultiplestrainsofHIV-1,HIV-2,andSIVbindtodendriticcellsviaDC-SIGN.DC-SIGNisexpressedinmucosaltissues,placenta,smallintestine,andrectum.
APPLICATIONSImmunoblotting:useat1-2ug/ml.Inimmunoblots,abandof44kDisdetected.
Positivecontrol:Humanplacentatissuelysate.
DiluteinPBSormediumwhichisidenticaltothatusedintheassaysystem.
Thisantibodyisstableforatleastone
(1)yearat-20oC.Avoidmultiplefreeze-thawcycles.
Forinvitroinvestigationaluseonly.Notforuseintherapeuticordiagnosticprocedures.


