Library Pack No. 100ug/clone

136101 All 4 clones

Library Pack No. 100ug/clone

136101 All 4 clones

ORDERING INFORMATION

Catalog No. Clone No. MAb Subtype Size

13601 CHYMO10-101.2 IgG1 100ug, 500ug

13602 CHYMO10-103.5 IgG1 100ug, 500ug

13603 CHYMO10-104.5 IgG1 100ug, 500ug

13604 CHYMO10-104.10 IgG1 100ug, 500ug

Format: Protein G-purified antibody in PBS, pH 7.4

BACKGROUND

Chymotrypsin is a proteolytic enzyme produced by the pancreas that acts in the duodenum. Chymotrypsin preferentially cleaves peptide amide bonds where the carboxyl side of the amide bond (the P1 position) is a large hydrophobic amino acid (tyrosine, tryptophan, and phenylalanine). These amino acids contain an aromatic ring in their sidechain that fits into a \'hydrophobic pocket\' (the S1 position) of the enzyme. The proenzyme chymotrypsinogen is activated by trypsin.

SPECIFICATION SUMMARY

Antigen: Purified human pancreatic chymotrypsin.

Host Species: Mouse

Specificity: These antibodies recognize human pancreatic chymotrypsin. They do not cross- react with human pancreatic trypsin.

APPLICATIONS

ELISA: These antibodies have been qualified for use in ELISA to detect human pancreatic chymotrypsin.

Immunohistochemistry: Catalog no. 13604 has been qualified for detecting human pancreatic chymotrypsin in paraffin-embedded tissue.

#13604, paraffin-embedded human pancreas.

DILUTION INSTRUCTIONS

Dilute in PBS or medium that is identical to that used in the assay system.

STORAGE AND STABILITY

These antibodies are stable for at least one (1) year at -20oC to -70oC. Store product in appropriate aliquots to avoid multiple freeze-thaw cycles.

For in vitro investigational use only. Not intended for use in therapeutic or diagnostic procedures.

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