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联系方式
公司地址
苏州工业园区生物纳米园A4#216
联系电话
4000-520-616 / 18915418616
传真号码
0512-67156496
电子邮箱
info@ebiomall.com
公司网址
https://www.ebiomall.com
商品描述
Cataloguenumber
PRO-2234
Synonyms
Decorin,BoneproteoglycanII,PG-S2,PG40,DCN.
Introduction
Decorin(DCN)isasmallcellularorpericellularmatrixproteoglycanwhichiscloselyrelatedinstructuretobiglycanprotein.Decorinisasecretedproteinwhichbindstocollagenandfibronectininextracellularmatrix.Decorinappearsindifferentglycoforms,substitutedwithchondroitinsulfateordermatansulfateconsistentwiththeoriginaltissue.DCNcontainsoneattachedglycosaminoglycanchain.Decorininfluencestherateoffibrilformation.Decoriniscapableofsuppressingthegrowthofvarioustumorcelllines.DCNgenedefectscausecornealdystrophy.TheDCNgeneisacandidategeneforMarfansyndrome.
Description
DCNproducedinSf9Baculoviruscellsisasingle,glycosylatedpolypeptidechain(17-354a.a.)andfusedtoa6aaHisTagatC-terminuscontainingatotalof344aminoacidsandhavingamolecularmassof38.8kDa.
DCNshowsmultiplebandsbetween40-57kDaonSDS-PAGE,reducingconditionsandpurifiedbyproprietarychromatographictechniques.
DCNshowsmultiplebandsbetween40-57kDaonSDS-PAGE,reducingconditionsandpurifiedbyproprietarychromatographictechniques.
Source
Sf9,Baculoviruscells.
PhysicalAppearance
Sterilefilteredcolorlesssolution.
Formulation
DCNproteinsolution(0.25mg/ml)containsPhosphatebufferedsaline(pH7.4),30%glyceroland 0.1mMPMSF.
StABIlity
Storeat4°Cifentirevialwillbeusedwithin2-4weeks.Store,frozenat-20°Cforlongerperiodsoftime.
Forlongtermstorageitisrecommendedtoaddacarrierprotein(0.1%HSAorBSA).
Avoidmultiplefreeze-thawcycles.
Forlongtermstorageitisrecommendedtoaddacarrierprotein(0.1%HSAorBSA).
Avoidmultiplefreeze-thawcycles.
Purity
Greaterthan90.0%asdeterminedbySDS-PAGE.
Aminoacidsequence
GPFEQRGLFDFMLEDEASGIIPYDPDNPLISMCPYRCQCHLRVVQCSDLGLDKVPWDFPPDTTLLDLQNNKITEIKEGAFKNLKDLHTLILVNNKISKISPEAFKPLVKLERLYLSKNQLKELPEKMPRTLQELRVHENEITKLRKSDFNGLNNVLVIELGGNPLKNSGIENGAFQGLKSLSYIRISDTNITAIPQGLPTSLTEVHLDGNKITKVDAPSLKGLINLSKLGLSFNSITVMENGSLANVPHLRELHLDNNKLLRVPAGLAQHKYIQVVYLHNNNISAVGQNDFCRAGHPSRKASYSAVSLYGNPVRYWEIFPNTFRCVYVRSAIQLGNYKHHHHHH
Usage
Prospec"sproductsarefurnishedforLABORATORYRESEARCHUSEONLY.Theproductmaynotbeusedasdrugs,agriculturalorpesticidalproducts,foodadditivesorhouseholdchemicals.


