神经组学/mGluR6/P13105/50 ul@2mgs/ml阻断肽

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¥1900.00
货号:P13105-50ul@2mgs/mlBlockingPeptide
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品牌:Neuromics
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商品描述

Type:RabbitIgG

 

Applications:ICC;IHC;WB

E=ELISA;FACS;FC=FlowCytometry;FPLC=FastProteinLiquidChromatography;GF=GravityFlow;HPLC=HighPerformanceLiquidChromatography;ICC=Immunocytochemistry;IF=Immunofluorescence;IHC=Immunohistochemistry;IP=Immunoprecipitation;NAC=Non-adherentCellAssays;NB=NeutralizationofBioactivity;SE=SandwichELISA;TPE=TargetedProteinExpression;WB=Westernblotting;;AC=AdherentCellAssays;FM=FluorescentMicsroscopy;;;BSC-CM5=BiacoreSensorChipCM5;BSM=BiosactiveSmallMoleculeorPeptide;CDM=CellDifferentiationMedia;;;;;;HealthandFitness;;;DNAExtraction/Purification;;InvivoLikeAssays

SpeciesReactivity:M;R

B=Bovine;Ca=Cat;Ch=Chicken;D=Dog;EQ=Equine;GP=GuineaPig;H=Human;M=Mouse;P=Porcine;Pr=Primate;R=Rat;Rb=Rabbit;Y=Yeast;Xe=Xenopus;Ze=Zebrafish;;;;NA-NotApplicable;STP=Step-TactinProteins;All

Format:AffinityPurified-liquid

 

Immunogen:AAPPQNENAEDAK

 

Picture[2]Picture[4]

Metabotropicglutamatereceptors(mGluRs)areG-proteincoupledreceptorsactivatedbyglutamate.Basedonsequencesimilarity,transductionmechanismsandagoNISTpotencies,mGluRsaresuBDividedintothreegroups:mGluR1/mGluR5,mGluR2/mGluR3,andmGluR4/mGluR6/mGluR7/mGluR8.mGluRsarewidelydistributedthroughoutthenervoussystemandareexpressedbybothneuronsandglialcells.mGluRshavebeensuggestedtoplayavarietyoffunctionalroles,amongwhichisinvolvementinsynapticplasticityunderlyinglearningandmemoryaswellaschronicpain.

IHCImage:Stainingofmousenobrescueretinalsections.  

WBImage:Mouseretinallysates.CourtesyofMeganA.Foreman,UniversityofBirmingham.

mGluR6-CustomerDataandPublications.

Note:forICCsee:DanaSpecht,Shu-BiaoWu,PaulTurner,PeterDearden,FrankKoentgen,UweWolfrum,MarionMaw,JohannHelmutBrandstatter,andSusannetomDieck.EffectsofPresynapticMutationsonaPostsynapticCacna1sCalciumChannelColocalizedwithmGluR6atMousePhotoreceptorRibbonSynapses. InvestigativeOphthalmology&VisualScience,February2009,Vol.50,No.2.
Note:Acustomerfoundabandinthe60-70kDarangecorrespondingtothemGluR6precursor.

 

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