神经组学/FOXN1/P41016/100微克

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¥2900.00
货号:P41016-100ug
浏览量:127
品牌:Neuromics
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商品描述

Type:GoatIgG

 

Applications:IHC;E

E=ELISA;FACS;FC=FlowCytometry;FPLC=FastProteinLiquidChromatography;GF=GravityFlow;HPLC=HighPerformanceLiquidChromatography;ICC=Immunocytochemistry;IF=Immunofluorescence;IHC=Immunohistochemistry;IP=Immunoprecipitation;NAC=Non-adherentCellAssays;NB=NeutralizationofBioactivity;SE=SandwichELISA;TPE=TargetedProteinExpression;WB=Westernblotting;;AC=AdherentCellAssays;FM=FluorescentMicsroscopy;;;BSC-CM5=BiacoreSensorChipCM5;BSM=BiosactiveSmallMoleculeorPeptide;CDM=CellDifferentiationMedia;;;;;;HealthandFitness;;;DNAExtraction/Purification;;InvivoLikeAssays

SpeciesReactivity:H

B=Bovine;Ca=Cat;Ch=Chicken;D=Dog;EQ=Equine;GP=GuineaPig;H=Human;M=Mouse;P=Porcine;Pr=Primate;R=Rat;Rb=Rabbit;Y=Yeast;Xe=Xenopus;Ze=Zebrafish;;;;NA-NotApplicable;STP=Step-TactinProteins;All

Format:AffinityPurified-liquid

 

Immunogen:PeptidewithsequenceC-SVYLSPSSKPVALA,fromtheCTerminusoftheFOXN1proteinaccordingtoNP_003584.2.

 

Picture

FOX1NorForkheadboxN1isinvovledinT-celldevelopment.Mutationsinthewinged-helixtranscriptionfactorgeneatthenudelocusinmiceandratsproducethepleiotropicphenotypeofhairlessnessandathymia,resultinginaseverelycompromisedimmunesystem.

Image:FOX1N(Dilution:20μg/ml)stainingofparaffinembeddedHumanThymusMedulla.SteamedantigenretrievalwithcitratebufferpH6,AP-staining.ProtocolonData-sheet.

DefectsinFOXN1arethecauseofT-cellimmunodeficiencycongenitalalopeciaandnaildystrophy.Adisordercharacterizedbytheassociationofcongenitalalopecia,severeT-cellimmunodeficiency,andridgingandpittingofallnails.

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