生命传感器/UB213-3摩尔UBE2E3/UB213-3摩尔UBE2E3

价格
¥3300.00
货号:UB213-3NMOLESUBE2E3
浏览量:48
品牌:Life Sensors
服务
全国联保
正品保证
正规发票
签订合同
商品描述

UBE2E3isanE2conjugationenzymethatisinvolvedintheubiquitylationoftargetsubstrates,alongwithE1andE3enzymes.Thededuced207-aminoacidproteinsharesover94%aminoacididentitywiththeUBCdomainsofclassIIIE2s,UbcH6,UBE2E2,UbcM2,UbcM3,andUbcD2.Ofthese,however,onlyUbcM2(thoughttobethemousehomologue)exhibitshomologyintheN-terminalextension.UBE2E3formsathioesterbondwithubiquitininanE1-dependentmannerandmediatesthetransferofubiquitinfromaubiquitin-activatingenzyme(E1)toasubstrateproteinorE3ligase.


Info


Amount3nmol
StateLiquid
MolecularWeight22,912.7Da
SourceHumanRecombinant
FusionTagNone
AccessionNumberQ969T4
AlternateNamesUbcH9,UbcM2,Ubce4
Storage-80°C,avoidfreeze/thawcycles
StABIlity1yearunderrecommendedstorageconditions
RecommendedUseEnzymeconcentrationof100nM–1mMisrecommendedfor invitro conjugation.



Applications

  • IdentifycognateE2/E3pairs
  • Characterizeupregulation/downregulationofE2enzymes
  • Buildpoly-ubiquitinchains
  • CharacterizeubiquitinchainspecificityofE2enzymes
  • AnalyzeexpressionofE2enzymes


Benefits

  • Untagged(native)E2conjugationenzyme


Documents

Lifesensors 是一家生物技术公司,致力于为治疗,药物发现和研究市场开发支持技术。通过提供创新的研究工具,确立了在泛素和类泛素蛋白途径中的先进地位。此外,我们的原核和真核蛋白表达平台 SUMOpro 和 SUMOstar 在世界范围内被学术、政府、制药和生物技术实体所使用