LifeSensors/AB140-125 µg Phospho-Ubiquitin (pS65) Polyclonal Antibody/AB-0140-0125

价格
¥7900.00
货号:AB-0140-0125
浏览量:127
品牌:Life Sensors
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商品描述

Specifications

Ubiquitin(Ub),ahighlyconserved,8kDapolypeptidepresentinalleukaryoticcells,isconjugatedtotheε-aminogroupoflysineresiduesinthetargetproteinthroughthesequentialactionofthreeenzymes,anE1Ubactivatingenzyme,anE2conjugatingenzyme,andanE3ligase.Inaddition,thesevenlysineswithinUbitselfcanserveasUbacceptorsleADIngtotheformationofpolyubiquitinchains.AmongtheseK48andK63linkagesarewellcharacterized.K48-linkedpolyubiquitylationtargetsproteinsforproteasomaldegradationwhereasK63linkagesregulatesignalingevents,receptorendocytosisandimmuneresponses.Polyubiquitinlinkagesatotherlysinesarelessprominentandtheirphysiologicalroleremainslargelyunknown.

Info

SpeciesRabbit
Purity>90%
IsotypeIgG1
Suppliedas125ugat1.25mg/mL
StorageStableforweeksat+4°C.Sodiumazidecanbeaddedtoanantibodypreparationtoafinalconcentration0.02%(w/v).Forlongtermstorage(6to12months)storeat-20°C.Avoidmultiplefreeze/thawcycles.
Lifesensors 是一家生物技术公司,致力于为治疗,药物发现和研究市场开发支持技术。通过提供创新的研究工具,确立了在泛素和类泛素蛋白途径中的先进地位。此外,我们的原核和真核蛋白表达平台 SUMOpro 和 SUMOstar 在世界范围内被学术、政府、制药和生物技术实体所使用