Accelagen/PAK2KD(重组人PAK2激酶结构域)/K0105B/块

价格
面议
货号:K0105B
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品牌:Accelagen
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商品描述
Description:
HumanPAK2kinase(UniProt:Q13177;NCBI:NM_002577)belongstoafamilyofp21-activatedkinases.Theseserine/threoninekinasesareregulatedbythesmallGTPbindingproteinsCdc42andRacandhavebeenimplicatedinawiderangeofBIOLOGicalactivities.PAK2isactivatedbyproteolyticcleavageduringcaspase-mediatedapoptosis,andmayplayaroleinregulatingtheapoptoticeventsinthedyingcell.

PAK2KDisarecombinantwildtypehumanPAK2kinasedomain(aminoacids227–524offull-lengthhumanPAK2)expressedinE.coliandpurifiedtonearhomogeneitywithhighspecificactivity.

MolecularMassandPhosphorylation:
Thecalculatedmassis33,510.PAK2KDisfullyphosphorylatedatT402andpartiallyphosphorylatedatadditionalsiteswithmeasuredmassof33,593(1P),33,673(2P),33,753(3P),and33,834(4P).

StABIlityandStorage:
Stableat-70oCfor12monthsfromdateofreceipt.Proteinshouldbethawedonice.Proteincanbeflash-frozeninliquidnitrogenandstoredat-70oC.

Applications:
Enzymaticstudies,inhibitorscreen,andselectivityprofiling
Highconcentrationavailableforcrystallization

Accelagen Accelagen 是一个快速成长起来的gene-to-protein公司。可提供gene-to-protein全方位解决方案。该公司生产的重组蛋白已经广泛应用于基 于结构的药物设计(SBDD)和高通量筛选(HTS)领域,Turbo3C(HRV3C)Protease, TurboTEV Protease, TurboNuclease是该公司极具性价比的优质产品。Accelagen重组蛋白表达和纯化服务可为生物学科研人员及药物研究提供高品质的重组蛋 白。

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