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联系方式
公司地址
苏州工业园区生物纳米园A4#216
联系电话
4000-520-616 / 18915418616
传真号码
0512-67156496
电子邮箱
info@ebiomall.com
公司网址
https://www.ebiomall.com
商品描述
MW:679.8Da
CASRegistry#:402957-28-2
Formula:C36H53N7O6
Description:
TelaprevirinhibitsthehepatitisCvirusNS3-4Aserineprotease,leADIngtotheblockofviralpolyproteinprocessing.ThiseventuallyleadstoadecreaseofviralRNAreplication,HCVRNAlevels,aswellasandproteinlevelsintheCon1(genotype1b)subgenomicHCVrepliconcells.Thisoccursinatime-anddose-dependentmanner.
Synonym(s):
VX-950
Purity:
≥98%
BIOLOGicalActivity:
Telaprevirshowsasignificanttime-dependentincreaseininhibitoryeffectonthereplicationofHCVRNAwithIC50valuesof574nM,488nM,210nMand139nMfor24,48,72and120hoursincubation,respectively.OnaverageitdisplaysanIC50of354nMandanaverageIC90of830nM,respectively,fromthreeindependentexperimentsusing48hoursincubation.
Solubility:
≥100mg/mlinDMSO<1 mg/ml in Water <1 mg/ml in Ethanol
Format:
Off-whitepowder
Storage/StABIlity:
Storeatorbelow–20°C.Solidformisstableatleast12monthsfromdateofreceipt,whenstoredasdirected.Donotstoreaqueoussolutionsformorethanoneday.
ScientificCategory:
Protease
ProductType:
Inhibitor
Datashownislot-specific.Contactusforspecificinformationonotherlots.


