avanti极性脂质/siRNA/DNA/1EA/640009-1EA输送系统

价格
¥13582.20
货号:640009-1EA
浏览量:127
品牌:avanti polar lipids
服务
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商品描述

640009 | siRNA Delivery Kit

Delivery System for siRNA/DNA


Info

siRNA Delivery Kit

Delivery System for siRNA/DNA

The self-assembly of custom-synthesized MVL5 and GMO with siRNA results in the formation of a double-gyroid bicontinuous inverted cubic phase with colocalized lipid/siRNA domains. The high charge density (due to MVL5) and positive Gaussian modulus of the GMO-containing membranes confer optimal electrostatic and elastic properties for endosomal escape, enabling efficient siRNA delivery and effective, specific gene silencing.

Data
Hygroscopic
No
Light Sensitive
No
Storage Temperature
-20°C
Downloads
  • Technical Data Sheet
  • Safety Data Sheet
References

Leal C, Ewert KK, Shirazi RS, Bouxsein NF, Safinya CR. Nanogyroids incorporating multivalent lipids: enhanced membrane charge density and pore forming ability for gene silencing. Langmuir. 2011 Jun 21;27(12):7691-7. doi: 10.1021/la200679x. Epub 2011 May 25. PMID: 21612245; PMCID: PMC3119580.

PubMed ID: 21612245
Certificates of Analysis
  • Certificate of Analysis(Lot No. 640009P-1EA-A-010and 5081-AA010)
  • Certificate of Analysis(Lot No. 640009P-1EA-A-010and 5081PAA010)
  • Certificate of Analysis(Lot No. 640009P-1EA-011and 5081PAA011)
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美国Avanti Polar Lipids Inc www.avantilipids.com Avanti Polar Lipids Inc, 是美国著名的磷脂类产品的生产商,该公司主要为各种制药厂和研究机构提供从毫克级到公斤级乃至吨级的磷脂类和甾体类中间体和试剂。 Avanti Polar Lipids.公司为世界范围内的研究机构和制药公司提供 1000 种以上脂类产品,由于其产品的高纯度而享誉全球, For 40 years, Avanti Polar Lipids, Inc. has been supplying lipids to researchers and pharmaceutical companies around the world. Not only has the range of products grown every year but so has Avanti’s unique reputation for purity. This brings us the satisfaction of our clients and the envy of our competitors. Avanti’s clients order from a stock of over 1,000 lipids at affordable prices. They enjoy working with our dedicated Customer Service representatives and benefit from our informed Technical Support team. Research clients are encouraged to contact us about custom synthesis of products not listed in our catalog. We are pleased to offer our Pharmaceutical clients products which follow cGMP guidelines. Avanti’s selection of chemicals and range of services for Research and Pharmaceutical applications include • Analytical Services • Bioactive Lipids • Biotinylated Lipids • Cationic Lipids • L-threo-Lac Cer (Caveolar Uptake Inhibitor) • Cholesterol, Plant & Animal Derived • Coenzyme A, Fluorescent & Fatty Acyl Derivatives • Deuterium Labeled Phospholipids & Sphingolipids • Eicosanoids (synthetic) • Extrusion Equipment for Liposome Preparation • Fluorescent Phospholipids & Sphingolipids • Glycosylated & Phosphorylated Sphingolipids • Kdo2 Lipid A (TLR 4 Agonist) • PHAD™ Synthetic Vaccine Adjuvant • Lipid Formulation • LPA, Cyclic LPA & LPA Analogues • LIPID MAPS Mass Spec Standards • Oxidized Lipids • Sterols, Oxysterols, Deuterated & Fluorescent Sterols • PIP’s, Polyunsaturated PIP3, & Fluorescent PIP’s • Phospholipids & Sphingolipids • Polymerizable Lipids, PEG-Lipids & Functionalized PEG’s • Prostaglandins (synthetic) • S1P/LPA Receptor Selective Agonists & Antagonists • Sphingosyl PE & PI