avanti polar lipids/Apocholic acid/5mg/700241P-5mg

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¥5108.00
货号:700241P-5mg
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品牌:avanti polar lipids
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700241 | Apocholic acid

8(14),5β-cholenoic acid-3α,12α-diol

Apocholic acid
Info

Apocholic acid

8(14),5β-cholenoic acid-3α,12α-diol

The human metabolite Apocholic Acid is an unsaturated bile acid (BA), that is a derivative of one of the primary BAs - cholic acid. The compound is a byproduct of mild dehydration of cholic acid. Apocholic acid salts and esters are called apocholates.

As a BA, Apocholic Acid is a physiological steroid molecule. BAs’ main function is to serve as detergents that emulsify fats and other sterols and thus promote their digestion and absorption in the small intestine.

Recently, the bio compounds have also been discovered to act as signaling molecules and participate in major metabolic pathways regulating glucose and energy, cholesterol, other BAs, and drug metabolism. On the other hand, BAs can also be quite cytotoxic, if their concentrations become elevated, which happens under certain pathological conditions.

Therein, Apocholic Acid also has some pathological abilities. This bile acid is believed to be related to some specific types of cancers. Its correlation with sarcoma is well-explored and established in experimental rat models.

Scientists have found some further effects of Apocholic Acid. The compound is a powerful complex enolizing agent that forms stable derivatives when linked to other organic molecules. Apocholic acid can decrease serum and liver cholesterol levels in rats, as well. It’s also often used as a dietary supplement for rats.

Avanti Polar Lipids produce pure and stable Apocholic Acid ready to advance your laboratory work and experiments in the field of lipids and BAs.

Data
Hygroscopic
No
Light Sensitive
No
Molecular Formula

C24H38O4

Percent Composition

C 73.81%, H 9.81%, O 16.39%

Purity
>99%
Stability
1 Year
Storage Temperature
-20°C
CAS Number
641-81-6 CAS Registry Number is a Registered Trademark of the American Chemical Society
FormulaWeight
390.56
Exact Mass
390.28
Downloads
  • ChemDraw File
  • 3D Structure
  • Structure
  • Safety Data Sheet
References
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美国Avanti Polar Lipids Inc www.avantilipids.com Avanti Polar Lipids Inc, 是美国著名的磷脂类产品的生产商,该公司主要为各种制药厂和研究机构提供从毫克级到公斤级乃至吨级的磷脂类和甾体类中间体和试剂。 Avanti Polar Lipids.公司为世界范围内的研究机构和制药公司提供 1000 种以上脂类产品,由于其产品的高纯度而享誉全球, For 40 years, Avanti Polar Lipids, Inc. has been supplying lipids to researchers and pharmaceutical companies around the world. Not only has the range of products grown every year but so has Avanti’s unique reputation for purity. This brings us the satisfaction of our clients and the envy of our competitors. Avanti’s clients order from a stock of over 1,000 lipids at affordable prices. They enjoy working with our dedicated Customer Service representatives and benefit from our informed Technical Support team. Research clients are encouraged to contact us about custom synthesis of products not listed in our catalog. We are pleased to offer our Pharmaceutical clients products which follow cGMP guidelines. Avanti’s selection of chemicals and range of services for Research and Pharmaceutical applications include • Analytical Services • Bioactive Lipids • Biotinylated Lipids • Cationic Lipids • L-threo-Lac Cer (Caveolar Uptake Inhibitor) • Cholesterol, Plant & Animal Derived • Coenzyme A, Fluorescent & Fatty Acyl Derivatives • Deuterium Labeled Phospholipids & Sphingolipids • Eicosanoids (synthetic) • Extrusion Equipment for Liposome Preparation • Fluorescent Phospholipids & Sphingolipids • Glycosylated & Phosphorylated Sphingolipids • Kdo2 Lipid A (TLR 4 Agonist) • PHAD™ Synthetic Vaccine Adjuvant • Lipid Formulation • LPA, Cyclic LPA & LPA Analogues • LIPID MAPS Mass Spec Standards • Oxidized Lipids • Sterols, Oxysterols, Deuterated & Fluorescent Sterols • PIP’s, Polyunsaturated PIP3, & Fluorescent PIP’s • Phospholipids & Sphingolipids • Polymerizable Lipids, PEG-Lipids & Functionalized PEG’s • Prostaglandins (synthetic) • S1P/LPA Receptor Selective Agonists & Antagonists • Sphingosyl PE & PI