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蚂蚁淘在线 / 品牌中心 / Usbio / Usbio/Erythropoietin alpha, Fc Chimera, Recombinant, Human (EPO-a, EPO-alpha, Epoetin)/2ug/299363
商品描述
This gene is a member of the EPO/TPO family and encodes a secreted, glycosylated cytokine composed of four alpha helical bundles. The protein is found in the plasma and regulates red cell production by promoting erythroid differentiation and initiating hemoglobin synthesis. This protein also has neuroprotective activity against a variety of potential brain injuries and antiapoptotic functions in several tissue types.||Erythropoietin-alpha Fc-Chimera Human Recombinant is produced in Chinese hamster ovary (CHO) cells by recombinant DNA technology is a dimeric, glycosylated, polypeptide chain consisting of two mature human EPO molecules linked to the Fc portion of human IgG1. The Fc component contains the CH2 domain, the CH3 domain and hinge region, but not the CH1 domain of IgG1. ||Source:|Recombinant protein corresponding to human EPO-a, consisting of two mature human EPO molecules linked to the Fc portion of human IgG1, expressed in CHO cells. ||Molecular Weight: |~140kD (non-reducing SDS-PAGE) ||Biological Activity:|The ED50, as determined by the dose-dependant stimulation of human megakaryoblastic leukemia cells, is <2ng/ml, corresponding to a specific activity of 5x10e5 IU/mg. ||Storage and Stability:|Lyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.Source: CHO cells|Purity: ~98% (RP-HPLC, SDS-PAGE)|Concentration: ~0.1mg/ml (after reconstitution)|Form: Supplied as a lyophilized powder in PBS, pH 7.4. No preservative added. Reconstitute with 100ug/ml sterile ddH2O. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). ||Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. USBio的生物化学品,抗体,重组蛋白,细胞培养基和分子生物学试剂盒几乎用于所有科学应用和环境,包括基因组研究,生物技术,药物开发和疾病诊断。USBio产品从经济实惠的研究数量到更大的批量可用于工艺开发和生产。我们的客户包括位于美国和国外的大多数*的制药和生物技术公司。


