IBL/Anti-Mouse C-ERC/Mesothelin (308) Rabbit IgG/JP28127/

价格
面议
货号:JP28127
浏览量:127
品牌:IBL
服务
全国联保
正品保证
正规发票
签订合同
商品描述
Quantity/Tests50µg
Species/Antigenmouse
Hostrabbit
Subclass/CloneIgG
TypePolyclonal
PurificationwithAntigenPeptide
LabelNo
RegulatoryStatus:Forresearchuseonly
Detailsfor: Anti-MouseC-ERC/Mesothelin(308)RabbitIgG
ERChasbeenidentifiedasageneshowingstrongerexpressionincancer-affectedrenaltissuethaninnormalrenaltissueinEkerrats(aratmodelofrenalcancer).ThehumanhomologueoftheproteinencodedbythisgeneiscalledMPF(megakaryocytepotentiatingfactor)ormesothelin.Thisproteinisdetectedprominentlyinmesothelialcells,andithasbeensuggestedbeinginvolvedinthedevelopmentofmesothelioma,makingitapromisingtumorMarker.Inhumans,involvementofthisproteinhasalsobeensuggestedinthedevelopmentofpancreatic,ovarianandpulmonarycancers,etc.TheproteinisexpressedasaGPIanchor-typemembraneousprotein(about71kDainmolecularweight),whichisthoughttobecleavedbyafurin-likeproteasetoyieldfragmentsabout31kDaofN-terminalsideandabout40kDaofC-terminalside.WethinkitishelpfulforresearchofERC/Mesothelinproteinandhavecharacterizedthe31kDafragmentasN-ERC/Mesothelinandthe40kDafragmentasC-ERC/Mesothelin.
ThisantibodyisrecognizesmouseC-ERC/Mesothelin.

DistributedbyIBLInternational
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