IBL/大鼠N-ERC/间皮素ELISA/JP27765/

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面议
货号:JP27765
浏览量:127
品牌:IBL
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Kitsize12x8
MethodELISA
Incubationtime1x1h,2x30min
Standardrange0.08-5ng/mL
Specimen/Volumes100µLserum,EDTAplasma,culturemedium
Substrate/isotopeTMB450nm
RegulatoryStatus:Forresearchuseonly
Detailsfor: RatN-ERC/MesothelinELISA
ERChasbeenidentifiedasageneshowingstrongerexpressionincancer-affectedrenalcellthaninnormalrenaltissueinEkerrats(aratmodelofrenalcancer).ThehumanhomologueoftheproteinencodedbythisgeneiscalledMPF(megakaryocytepotentiatingfactor)ormesothelin.Thisproteinismainlydetectedinmesothelialcells,anditsinvolvementinthedevelopmentofmesotheliomahasbeensuggested,makingitapromisingtumorMarker.Inhumans,involvementofthisproteinhasalsobeensuggestedinthedevelopmentof
pancreatic,ovarianandpulmonarycancers,etc.TheproteinisexpressedasaGPIanchor-typemembranousprotein(about71kDainmolecularweight),whichisthoughttobedigestedbyafurin-likeproteasetoyieldfragmentsabout31kDaand40kDainsize.

Wehaveestablishedasystemfortheassayofthisprotein,referringtothe31kDafragmentasN-ERC/Mesothelinand40kDafragmentasC-ERC/Mesothelin.Thekit,anELISAkitdesignedforthedeterminationofN-ERC/MesothelinandisaimedatanalyzingtheexpressionofERCindetailusingtumorcelllines,serumandplasma.

Separatecontrolsetavailableonrequest
ForconcretedatapleaseconsulttheInstructionforUseinthedownloadboxontherightside.
iBL的Tecan由四名工程师于1980年在瑞士Hombrechtikon村成立,旨在开发测量,分析和实验室自动化设备。最初的办公室位于经过翻新的农舍中,这是首席执行官兼创始人亨氏·阿普兰纳普(Heinz Abplanalp)的家庭住宅。