IBL/sICAM-1 (monkey) ELISA/BE45711/

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面议
货号:BE45711
浏览量:127
品牌:IBL
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商品描述
Kitsize12x8
MethodELISA
Incubationtime1x1h,1x10min
Standardrange6.25-100U/mL
Specimen/Volumes25µLserum,plasma,cellculturesupernatantetal.
Substrate/isotopeTMB450nm
RegulatoryStatus:Forresearchuseonly
Detailsfor: sICAM-1(monkey)ELISA
IntercellularAdhesionMolecule-1(ICAM-1)isamemberoftheimmunoglobulinsupergenefamilyandfunctionsasaligandfortheLymphocyteFunction-AssociatedAntigen-1(LFA-1),analpha-beta-complexthatisamemberoftheleukocyteintegrinfamilyofcell-cellandcell-matrixreceptors.ThisfamilyconsistsoftheleukocyteadhesionglycoproteinsLFA-1whichmediateslymphocyteadhesion,Mac-1whichmediatesgranulocyteadhesionandp150,95.ICAM-1isasingle-chainglycoproteinwithapolypeptidecorethatcanbeexpressedonnon-hematopoieticcellsofmanylineagessuchasvascularendothelialcells,thymicepithelialcells,otherepithelialcellsandfibroblastsandonhematopoieticcellssuchastissuemacrophages,mitogen-stimulatedT-lymphoblasts,germinalcenterB-cellsanddendriticcellsintonsils,lymphnodesandPeyer"spatches.ICAM-1isinducIBLeonfibroblastsandendothelialcellsbyinflammatorymediatorssuchasIL-1,TNFandIFN-gammawithinfewhoursandiscorrelatedtotheinfiltrationoflymphocytesintoinflammatorylesions.ICAM-1seemstobetheinitialMarkerofinflammatoryreactionsandisexpressedpriorto,andtoagreaterextentthanisHLA-DR.TheroleofICAM-1asadiseasemarkerhasbeendemonstratedforanumberofdifferentindicationsandpathologicalsituations.

Synonyms:Intercellularadhesionmolecule1,CD54antigen
ForconcretedatapleaseconsulttheInstructionforUseinthedownloadboxontherightside.
iBL的Tecan由四名工程师于1980年在瑞士Hombrechtikon村成立,旨在开发测量,分析和实验室自动化设备。最初的办公室位于经过翻新的农舍中,这是首席执行官兼创始人亨氏·阿普兰纳普(Heinz Abplanalp)的家庭住宅。