IBL/IL-8/IL-8(猴)ELISA/BE45581/

价格
面议
货号:BE45581
浏览量:127
品牌:IBL
服务
全国联保
正品保证
正规发票
签订合同
商品描述
Kitsize12x8
MethodELISA
Incubationtime1x2h,1x10min
Standardrange19-1250U/mL
Specimen/Volumes50µLserum,plasma,cellculturesupernatantetal.
Substrate/isotopeTMB450nm
RegulatoryStatus:Forresearchuseonly
Detailsfor: Interleukin-8/IL-8(monkey)ELISA
Interleukin-8selectivelystimulatestheABIlityofneutrophilsandT-lymphocytestoinvadeinjuredorinflamedtissue.IL-8alsoknownasCXCL8thatispurifiedfromperipheralbloodmonocytesisa10kDaproteinshowingatleast4variantforms(77,72,70,and69aminoacids,respectively)whichdifferinthelengthoftheN-terminalandreADIlyformdimersinsolution.Twocystin-bridgesareessentialfortheBIOLOGicalactivityofIL-8.ExogenousstimulilikeLPS,butalsoIL-1,TNF-alphaandTNF-betainducethesecretionofIL-8inavarietyofdifferentcelltypesincludingmonocytes,endothelialandepithelialcells,peripheralbloodmononuclearcells,dermalfibroblasts,keratinocytes,neutrophils,hepatocytes,synovialcells,andT-lymphocytes.TheactivitiesofIL-8arenotspecies-specific.HumanIL-8isalsoactiveinrodentandrabbitcellsanddiffersfromallothercytokinesinitsabilitytospecificallyactivateneutrophilgranulocytes.Thischemokineactivatesmultipleintracellularsignalingpathwaysdownstreamoftwocell-surface,Gprotein-coupledreceptors(CXCR1andCXCR2).ThepropertyofIL-8tostimulatemovementofneutrophilsacrossendothelialmonolayersinvitrosupportstheconceptofacentralroleforthismoleculeintheaccumulationofneutrophilsatinflammatorylesionsinvivo.

Synonyms:Protein3-10C,CXCL8,NAP-1,GCP-1
ForconcretedatapleaseconsulttheInstructionforUseinthedownloadboxontherightside.
iBL的Tecan由四名工程师于1980年在瑞士Hombrechtikon村成立,旨在开发测量,分析和实验室自动化设备。最初的办公室位于经过翻新的农舍中,这是首席执行官兼创始人亨氏·阿普兰纳普(Heinz Abplanalp)的家庭住宅。