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公司地址
苏州工业园区生物纳米园A4#216
联系电话
4000-520-616 / 18915418616
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0512-67156496
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info@ebiomall.com
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商品描述
| Kitsize | 12x8 |
| Method | ELISA |
| Incubationtime | 1x2h,1x1h,1x30min |
| Standardrange | 3.9-250pg/mL |
| Specimen/Volumes | 50µLserum,plasma,cellculturesupernatantetal. |
| Substrate/isotope | TMB450nm |
| RegulatoryStatus: | Forresearchuseonly |
Detailsfor:Interleukin-17AF/IL-17AF(mouse)ELISA
iBL的Tecan由四名工程师于1980年在瑞士Hombrechtikon村成立,旨在开发测量,分析和实验室自动化设备。最初的办公室位于经过翻新的农舍中,这是首席执行官兼创始人亨氏·阿普兰纳普(Heinz Abplanalp)的家庭住宅。 IL-17AandIL-17FaremembersoftheIL-17familyandsignatureTh17cytokines.OfthesixIL-17familymembers,IL-17FandIL-17Asharethestrongesthomology(50%aminoacididentity)andthetwogenesarelocatedinthesamechromosomalregion.AlthoughbothIL-17AandIL-17Fwereoriginallyfoundtobeproducedasdisulfide-linkedhomodimers,recentstudieshaveconfirmedtheproductionofIL-17AFheterodimersininvitro-differentiatedandpolarizedTh17cells.ActivatedhumanCD4+TcellsinculturewerefoundtosecretetheIL-17Fhomodimerat10-foldhigherlevelsthantheIL-17Ahomodimer,suggestingthatthemajorityoftheIL-17AproteinexpressedexistsintheformoftheIL-17AFheterodimer.StudiesofTh17-polarizedmousesplenocytesalsoindicatethatthemajorityofIL-17producediscomplexedastheIL-17AFheterodimer.IL-17FandIL-17Ahavebeenobservedintissuesamplesfromvariousautoimmunediseases,suchasrheumatoidarthritis,multiplesclerosis,psoriasis,inflammatoryboweldisease,andasthma.
Synonyms:Interleukin17AF,IL-17A/Fheterodimer
ForconcretedatapleaseconsulttheInstructionforUseinthedownloadboxontherightside.Synonyms:Interleukin17AF,IL-17A/Fheterodimer


