Tocris/SCH 442416/2463/50/50 mg

价格
¥16500.00
货号:2463/50
浏览量:127
品牌:Tocris
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商品描述
Description:Veryselective,highaffinityA2AantagoNIST
ChemicalName:2-(2-Furanyl)-7-[3-(4-methoxyphenyl)propyl]-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

SelectiveadenosineA2Areceptorantagonist;bindstohumanandratA2Areceptorswithhighaffinity(Kivaluesare0.048and0.5nMrespectively).Displays>23000-foldselectivityforhA2AoverhA1invitrowithminimalaffinityforhA2BandhA3receptors(IC50>10μM).BlocksthecytoprotectiveeffectofA2AagonistCGS-21680(Cat.No.1063).

TechnicalData

M.Wt389.42
FormulaC20H19N7O2
StorageStoreatRT
Purity≥99%(HPLC)
CASNumber316173-57-6
PubChemID10668061
InChIKeyAEULVFLPCJOBCE-UHFFFAOYSA-N
SmilesCOC1=CC=C(CCCN2N=CC3=C2N=C(N)N2N=C(N=C32)C2=CC=CO2)C=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO38.94100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight389.42.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.57mL12.84mL25.68mL
5mM0.51mL2.57mL5.14mL
10mM0.26mL1.28mL2.57mL
50mM0.05mL0.26mL0.51mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet