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蚂蚁淘在线 / 品牌中心 / Tocris / Tocris/BAY 60-6583/4472/10/10 mg

Tocris/BAY 60-6583/4472/10/10 mg

价格
￥3700.00
货号：4472/10
浏览量：127
品牌：Tocris
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商品描述
Description:PotentA2BreceptoragoNIST;cardioprotective
ChemicalName:2-[[6-Amino-3,5-dicyano-4-[4-(cyclopropylmethoxy)phenyl]-2-pyridinyl]thio]-acetamide
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentadenosineA2Breceptoragonist(EC50=2.83nMformurineA2Breceptor).DisplaysselectivityforA2BoverA1,A2AandA3receptors.DecreasesfMLP-inducedsuperoxideproductioninneutrophilsatlowconcentrations(1-10nM).Cardioprotective;attenuatesinfarctsizeinamousemodelofmyocardialischemia.

CompoundLibraries

BAY60-6583isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt379.44
FormulaC19H17N5O2S
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber910487-58-0
PubChemID11717831
InChIKeyZTYHZMAZUWOXNC-UHFFFAOYSA-N
SmilesNC1=NC(SCC(N)=O)=C(C#N)C(C2=CC=C(OCC3CC3)C=C2)=C1C#N

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO37.94100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight379.44.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.64mL13.18mL26.35mL
5mM0.53mL2.64mL5.27mL
10mM0.26mL1.32mL2.64mL
50mM0.05mL0.26mL0.53mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet