Phenylmethylsulfonyl fluoride; Benzylsulfonyl fluoride

P-2401

329-98-6

Phenylmethanesulfonyl fluoride

C₇H₇FO₂S

174.2 Da

White fine needles/crystalline powder

≥98.5 %

Soluble in 10% pure ethanol, chloroform and diethyl ether. Clear, colorless solution in chloroform and diethyl ether.

PMSF has limited water solubility, it must be dissolved in a small amount of solvent, such as ethanol.

93.8°C

Dissolve PMSF in isopropanol at 1.74 mg/mL (10 mM); store in aliquots at -20°C

4°C, desiccated

Analgesic

PMSF inhibits serine proteases such as trypsin and chymotrypsin. Also inhibits cysteine proteases (reversible by reduced thiols) and mammalian acetylcholinesterase. It has been used in following applications; cell fractionation, a supplement in nuclear protein extraction, inhibitor of cholesterol esterase (CE) and pseudocholinesterase (PCE) and for the collection of blood prior to centrifugation to quantify plasma ANP levels.

N/A

MFCD00007424

X1032413-5

InChI=1S/C7H7FO2S/c8-11(9,10)6-7-4-2-1-3-5-7/h1-5H,6H2

c1ccc(cc1)CS(=O)(=O)F

Not Applicable

XT8040000

UN 2928

II

Not Applicable

Use only in area provided with appropriate exhaust ventilation. Keep away from heat and source of ignition. Empty containers pose a fire risk, evaporate residue under fume hood. Ground all equipment containing material. Do not breathe dust.

P-2401, PMSF, SDS, diamond format.pdf

P-2401, H1328C.pdf

P-2401, H1328B.pdf

P-2401, H1328A.pdf