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DiIC18(3);1,1′-dioctadecyl-3,3,3′,3′-tetramethylindocarbocyanine
DiIisawidelyusedcarbocyaninemembranedyethatlabelscellmembranesbyinsertingitstwolong(C18carbon)hydrocarbonchainsintothelipidbilayer.Particularly,ithasbeenextensivelyusedfortheanterogradeandretrogradelabelingofneurons.TheintensefluorescenceandhighphotostABIlityofthedyemakeitpossIBLetovisualizethefinestructures(axonsanddendrites)oftheneurons.Duetoitslowtoxicityandthetendencytogivehighlystablecelllabeling,thedyehasalsobeengenerallyusedforlongtermcelltracingofcellsbothinculturesandinlivingembryosoranimals.Pleasealsoseeourready-to-useCellBrite™CellMembraneLabelingSolutions.
- λEx/λEm(MeOH)=549/565nm
- ε=148,000
- Darkredsolidsolubleinethanol,DMForDMSO
- Storeat-20°C
- C59H97ClN2O4
- MW:933.88
- [41085-99-8]
References
1.Biochemistry19,6050(1980).
2.J.
Immunology127,893(1981).
3.Trends
inNeurosci9,333(1989).
4.JCellBiol103,171(1986).


