ThisassaymeasuresPKlevelinvarioustypesofsamples,includingcells,serum,plasma,andtissue.Thisproductisforresearchpurposesonlyandisnotapprovedforuseinanimals,humans,ordiagnosticprocedures.
Pyruvatekinase(PK)isanenzymethatcatalyzesthefinalstepofglycolysis,thetransferofaphosphategroupfromphospho(enol)pyruvatetoADP,yieldingpyruvateandATP.Pyruvatekinasecanregulategluconeogenesisandadditionally,pyruvatekinasedeficiencyisthesecondmostcommoncauseofhemolyticanemia.Thiscolorimetricassayisbasedonpyruvatekinase-catalyzedformationofpyruvate,whichcanbefurtheroxidized,wheretheformedhydrogenperoxideiscatalyzedbyperoxidaseandreactswith4-aminoantipyrinetoformacoloredproduct.Theintensityofthecoloredreactionproduct,whichexhibitsmaximumabsorbanceat570nm,isdirectlyproportionaltotheactivityofpyruvatekinaseinthesample.

Specifications:

CatalogNo.	8628
CountryofManufacture	UnitedStates
ProductCode	PK
Size/Quantity	100Tests
ProductUse	ThisassaymeasuresPKlevelinvarioustypesofsamples,includingcells,serum,plasma,andtissue.Thisproductisforresearchpurposesonlyandisnotapprovedforuseinanimals,humans,ordiagnosticprocedures.
Storage	Storein-20°C
ShippingInfo	Shippedondryice.

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