Thisassaykitisusedtoevaluatetubeformationinvitro.Itisforresearchuseonly.Notforuseinanimals,humans,ordiagnosticprocedures.
Angiogenesis,ortheformationofnewbloodvessels,playsanimportantroleinmanyphysiological(e.g.woundhealing)andpathological(e.g.tumorgrowthandinflammationdisease)processes.Asacomplexmulti-stepprocess,angiogenesisinvolvesdegradationofbasementmembrane,proliferationandmigrationofendothelialcellsintoextracellularmatrix(ECM),followedbyalignmentandreorganizationofendothelialcellsintothree-dimensionaltubularstructureandformationofnewbasementmembrane.Specifically,thecriticalstepoftheformationofthree-dimensionaltubularstructurebyendothelialcellsistheobjectiveofmanyinvivoandinvitroangiogenesisassaystoscreenefficacyofbothpro-andantiangiogenicagents.TheSciencellInVitroTubeFormationAssayprovidesaconvenientsystemtomeasuretheformationofthree-dimensionaltubularstructurebyenodothelialcellswhenculturedonanECMgelofbasementmembraneextract.TheECMgel,whichispreparedfromEngelbrethHolm-Swarm(EHS)sarcomaproducedinmice,consistsoflaminin,collagenIV,heparansulfateproteoglycan,entactinandotherminorcomponentsoptimizedfortubeformation.Withthissystem,tubeformationcanbeachievedwithin6-18hours,withtheearliestsignsoftubularstructureshownupafter3-4hours.TheAssayalsoprovidesacolorimetriccellstainingreagentforbetterexamination.

Specifications:

CatalogNo.	8158
CountryofManufacture	UnitedStates
ProductCode	IVTFA
Size/Quantity	50tests
ProductUse	Thisassaykitisusedtoevaluatetubeformationinvitro.Itisforresearchuseonly.Notforuseinanimals,humans,ordiagnosticprocedures.
Storage	-20°C
ShippingInfo	Dryice.

SciencCell公司 是1999年成立于美国洛杉矶圣地亚哥，是一家快速成长的生物技术公司，其一直专注于是研发实验和治疗相关的细胞产品。ScienCell公司提供多种多样、高质量的人和动物的原代细胞，原代细胞培养基、干细胞研究相关领域产品和相关试剂。