Description: HumanPAK7kinase(UniProt:Q9P286;NCBI:NM_177990)belongstoafamilyofp21-activatedkinases.Theseserine/threoninekinasesareregulatedbythesmallGTPbindingproteinsCdc42andRacandhavebeenimplicatedinawiderangeofBIOLOGicalactivities.PAK7(PAK5)ispredominantlyexpressedinbrain.Itiscapableofpromotingneuriteoutgrowthandcellsurvival.PAK7KD(PAK5KD)isarecombinantwildtypehumanPAK7kinasedomain(aminoacids425–719offull-lengthhumanPAK7)expressedinE.coliandpurifiedtohomogeneitywithfullactivity. MolecularMassandPhosphorylation: Thecalculatedmassis33,934.PAK7KDisfullyphosphorylatedatS602andanadditionalsitewithameasuredmassof34,096(2P). StABIlityandStorage: Stableat-70oCfor12monthsfromdateofreceipt.Proteinshouldbethawedonice.Proteincanbeflash-frozeninliquidnitrogenandstoredat-70oC. Applications: Enzymaticstudies,inhibitorscreen,andselectivityprofiling Highconcentrationavailableforcrystallization

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