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联系方式
公司地址
苏州工业园区生物纳米园A4#216
联系电话
4000-520-616 / 18915418616
传真号码
0512-67156496
电子邮箱
info@ebiomall.com
公司网址
https://www.ebiomall.com
商品描述
MW: 338.2 Da
CAS Registry #: 1314241-44-5
Formula: C15H20BrN3O
Target: L3MBTL1
Description:
UNC669 is a potent and selective MBT (malignant brain tumor) inhibitor for L3MBTL1.
Synonym(s):
(5-bromopyridin-3-yl)-(4-pyrrolidin-1-ylpiperidin-1-yl)methanone
Purity:
≥98% by HPLC
Biological Activity:
Small molecule antagonist of methyl-lysine (KMe) reader protein with selectivity for L3MBTL1 and L3MBTL3 (IC50 of 4.2 µM and 3.1 µM respectively). An earlier publication reported a 5- and 11-fold selectivity of L3MBTL1 (IC50 = 6 µM )over L3MBTL3 (IC50 = 35 µM )and L3MBTL4 (IC50 > 70 µM).
Solubility:
Soluble in DMSO
Storage / Stability:
Store at or below –20°C. Solid form is stable at least 12 months from date of receipt, when stored as directed. Do not store aqueous solutions for more than one day.
Scientific Category:
Methyl-Lysine Reader Inhibitor
Product Type:
Inhibitor
Data shown is lot-specific. Contact us for specific information on other lots.


