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公司地址
苏州工业园区生物纳米园A4#216
联系电话
4000-520-616 / 18915418616
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0512-67156496
电子邮箱
info@ebiomall.com
公司网址
https://www.ebiomall.com
商品描述
Description:Potent,highaffinity5-HT2AagoNIST
ChemicalName:(4-Bromo-3,6-dimethoxybenzocyclobuten-1-yl)methylaminehydrobromide
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
Highaffinity5-HT2Areceptoragonist(Kivaluesare0.73and0.75nMforratandhumanreceptorsrespectively).PotentlystimulatesIP3accumulationinNIH3T3cellsstablyexpressingrat5-HT2Areceptors(EC50=36nM).Inducesheadtwitchesandhypothermiainmicefollowingi.p.adminitration.
CompoundLibraries
TCB-2isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
TechnicalData
| M.Wt | 353.05 |
| Formula | C11H14BrNO2.HBr |
| Storage | Storeat+4°C |
| Purity | ≥99%(HPLC) |
| CASNumber | 912342-28-0 |
| PubChemID | 71433791 |
| InChIKey | TYMMXVZAUGQKRF-UHFFFAOYSA-N |
| Smiles | Br.COC1=C2C(CN)CC2=C(OC)C(Br)=C1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 35.3 | 100 | |
| ethanol | 4.33 | 10 | |
| water | 8.83 | 25 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight353.05.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 2.83mL | 14.16mL | 28.32mL |
| 5mM | 0.57mL | 2.83mL | 5.66mL |
| 10mM | 0.28mL | 1.42mL | 2.83mL |
| 50mM | 0.06mL | 0.28mL | 0.57mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet
