Tocris蚂蚁淘在线

PotentandselectivePPARγagonist(EC₅₀=60nM);exhibitsnoactivityatPPARαandPPARβ.PromotesdifferentiationofpluripotentC3H10T1/2stemcellsintoADIpocytes.Exhibitsantihyperglycemicactivityindiabeticob/obmousemodel.Antidiabeticagent.

CompoundLibraries

RosiglitazoneisalsoofferedaspartoftheTocriscreenPlusandTocriscreenLibraryofFDA-ApprovedCompounds.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	357.43
Formula	C₁₈H₁₉N₃O₃S
Storage	Storeat+4°C
Purity	≥99%(HPLC)
CASNumber	122320-73-4
PubChemID	77999
InChIKey	YASAKCUCGLMORW-UHFFFAOYSA-N
Smiles	CN(CCOC1=CC=C(CC2SC(NC2=O)=O)C=C1)C3=CC=CC=N3

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	1eq.HCl	35.74	100
	DMSO	35.74	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight357.43.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.8mL	13.99mL	27.98mL
5mM	0.56mL	2.8mL	5.6mL
10mM	0.28mL	1.4mL	2.8mL
50mM	0.06mL	0.28mL	0.56mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

SafetyDatasheet

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托克里斯/罗格列酮/5325/50/50毫克

BiologicalActivity

CompoundLibraries

TechnicalData

SolubilityData

PreparingStockSolutions

MolarityCalculator

ReconstitutionCalculator

DilutionCalculator

ProductDatasheets