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联系方式
公司地址
苏州工业园区生物纳米园A4#216
联系电话
4000-520-616 / 18915418616
传真号码
0512-67156496
电子邮箱
info@ebiomall.com
公司网址
https://www.ebiomall.com
商品描述
Description:ERαantagoNIST;alsoactivatesunfoldedproteinresponse;activeinvivo
ChemicalName:1,3-Dihydro-3,3-bis(4-hydroxyphenyl)-7-methyl-2H-indol-2-one
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
Estrogenreceptor(ER)αinhibitor.Inhibitsproliferationofdrug-resistantERα-positivebreastandovariancancercells.Inducessustainedactivationoftheunfoldedproteinresponse.Activeinvivo.
TechnicalData
| M.Wt | 331.36 |
| Formula | C21H17NO3 |
| Storage | Storeat-20°C |
| Purity | ≥98%(HPLC) |
| CASNumber | 56632-39-4 |
| PubChemID | 3860640 |
| InChIKey | FABLAHMQSQFDHR-UHFFFAOYSA-N |
| Smiles | CC1=CC=CC2=C1NC(C2(C3=CC=C(C=C3)O)C4=CC=C(C=C4)O)=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 33.14 | 100 | |
| ethanol | 33.14 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight331.36.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 3.02mL | 15.09mL | 30.18mL |
| 5mM | 0.6mL | 3.02mL | 6.04mL |
| 10mM | 0.3mL | 1.51mL | 3.02mL |
| 50mM | 0.06mL | 0.3mL | 0.6mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
Thereconstitutioncalculatorallowsyoutoquicklycalculatethevolumeofareagenttoreconstituteyourvial.Simplyenterthemassofreagentandthetargetconcentrationandthecalculatorwilldeterminetherest.