多克隆抗体

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货号:E-AB-30021
抗体英文名:Cleaved-Caspase-4p20(Q81)PolyclonalAntibody
应用范围:WB,IHC-p,ELISA
宿主:Rabbit
适应物种:Human
克隆性:
保存条件:Storeat-20℃.Avoidfreeze/thawcycles.
亚型:IgG
免疫原:SynthesizedpeptidederivedfromtheInternalregionofhumanCaspase-4p20
规格:30μL/60μL/120μL

Overview

SynonymsCASP4,ICH2,Caspase-4,CASP-4,ICE(rel)-II,ProteaseICH-2,ProteaseTX
SwissprotP49662
SourceRabbit
ReactivityHuman
ImmunogenSynthesizedpeptidederivedfromtheInternalregionofhumanCaspase-4p20
ApplicationWB,IHC-p,ELISA
RecommendeddilutionWB1:500-1:2000,IHC1:100-1:300,ELISA1:40000
Concentration1mg/mL
ClonalityPolyclonal

Properties

IsotypeIgG
PurificationAffinitypurification
ConjugationUnconjugated
StorageinstructionsStoreat-20℃.Avoidfreeze/thawcycles.
StoragebufferPBSwith0.02%sodiumazide,0.5%BSAand50%glycerol,pH7.4
BackgroundThisgeneencodesamemberofthecysteineproteasesthatplaysimportantrolesinapoptosis,cellmigrationandtheinflammatoryresponse.Theencodedproteinmediatesproductionofpro-inflammatorycytokinesbymacrophagesuponbacterialinfection.Micelackingtheencodedproteinareresistanttoendotoxicshockinducedbylipopolysaccharide.A5-bpdeletionencompassingaspliceacceptorjunctionresultinginalternatesplicingandashorternon-functionalisoformincertainmousestrainshasbeendescribed.Althoughitsofficialnomenclatureis"caspase4,apoptosis-relatedcysteinepeptidase",thisgeneanditsencodedproteinhavehistoricallybeencalledcaspase11.Thisgeneispresentinaclusterofthreecaspasegenesonchromosome9.

Images


WesternBlotanalysisof3T3cellsusingCleaved-Caspase-4p20(Q81)PolyclonalAntibodyatdilutionof1:2000.
温馨提示:不可用于临床治疗。

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