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联系方式
公司地址
苏州工业园区生物纳米园A4#216
联系电话
4000-520-616 / 18915418616
传真号码
0512-67156496
电子邮箱
info@ebiomall.com
公司网址
https://www.ebiomall.com
商品描述
Target:
Chromogranin-B (C-term)
Target background:
Chromogranin-B is a prohormone and a member of the secretory granin family found in mammalian neuroendocrine cells. Although Chromogranin-B shares certain homology and binding properties with family member Chromogranin-A, the two proteins are thought to be mostly segregated in secretory granules. Chromogranin-B may be cleaved into multiple different peptides, some with identified biological activity. Recent research has indicated that Chromogranin-B may serve as a biomarker for heart failure in patients.
Target alias:
bCGB, Secretogranin I,
Immunogen:
C-terminal peptide (AA 547-560)
Specificity: The antibody recognizes an epitope in C-terminal (AA 547-560) of Chromogranine-B
Clone ID:
---
Preservative:
None
Format:
Lyophilized serum
Recommend starting dilution:
If reconstituted with deionized water in 100 µl: WB 1:2000. Optimal dilution has to be determined by the user.
Limitations:
Research Use Only
References:
1.-Fournier I - Processing of chromogranins/secretogranin in patients with diabetic retinopathy.
2.-Zhang D - Two chromogranin a-derived peptides induce calcium entry in human neutrophils by calmodulin-regulated calcium independent phospholipase A2.
3.-Zhang D - Two chromogranin a-derived peptides induce calcium entry in human neutrophils by calmodulin-regulated calcium independent phospholipase A2.
Storage:
Lyophilized antibodies can be kept at 4ºC for up to 3 months and should be kept at -20ºC for long-term storage (2 years). To avoid freeze-thaw cycles, reconstituted antibodies should be aliquoted before freezing for long-term (1 year) storage (-80ºC) or kept at 4ºC for short-term usage (2 months). For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made with the assay buffer. After the maximum long-term storage period (2 years lyophilized or 1 year reconstituted) antibodies should be tested in your assay with a standard sample to verify if you have noticed any decrease in their efficacy.


