Product Specification:
| Alternative Name: | Proteasome inhibitor 31 |
| Host: | Rabbit |
| Immunogen: | Synthetic peptide corresponding to aa 241-271 of C-terminal of human PI31. |
| UniProt ID: | Q92530 |
| Species reactivity: | Human, Mouse |
| Applications: | WB |
| Formulation: | Liquid. In PBS containing 10mM sodium azide. |
| Shipping: | Shipped on Blue Ice |
| Long Term Storage: | -20°C |
| Scientific Background: | Recombinant PI31 has been shown to compete with the proteasome regulators PA28 and 19S PA700 for binding to 20S, indicating that PI31 binds the 20S α-rings and may function by hindering substrate access to the 20S catalytic channel. |
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