吸气肌/特异性旋回蛋白结构域/0.5 mg/B24005

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货号:B24005
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品牌:inspiralis
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Specific Gyrase Protein Domains

All our gyrase subunits are supplied at a concentration of 1 mg/ml unless otherwise specified and are purified to > 95% as assessed by SDS-PAGE. We have an extensive collection of mutants not listed here so please contact us for a full list. Different quantities and concentrations can be supplied on request.

Click on the product headings below to view details and order online.

Gyrase Subunits

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For studies involving mutant drug-resistant E. coli gyrase subunits the wild-type subunits are available separately in the following amounts. The subunits are supplied at a concentration of 1 mg/ml, purified to > 95% as assessed by SDS-PAGE. Other quantities and concentrations are available as are the individual subunits from S. aureus and M. tuberculosis gyrases; please enquire for further information.

gyrase subunit 1

Technical Documents

Cat No.ProductPriceQuantity
SUBA001E. coli Gyrase A0.1 mgPOA
SUBA005E. coli Gyrase A0.5 mgPOA
SUBA100E. coli Gyrase A1.0 mgPOA
SUBB001E. coli Gyrase B0.1 mgPOA
SUBB005E. coli Gyrase B0.5 mgPOA
SUBB100E. coli Gyrase B1.0 mgPOA
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Purified Gyrase Domains

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For structural studies the following E. coli gyrase domains are available: GyrB43, GyrB24 and GyrA59. Domains supplied at a concentration of 1 mg/ml purified to > 95% as assessed by SDS-PAGE. (see gel below for typical levels of purity)

Larger quantities/different concentrations are available, please enquire.

gyrase subunit 2

Technical Documents

Cat No.ProductPriceQuantity
A59001Gyrase A590.1 mgPOA
A59005Gyrase A590.5 mgPOA
A59100Gyrase A591.0 mgPOA
B43001Gyrase B430.1 mgPOA
B43005Gyrase B430.5 mgPOA
B43100Gyrase B431.0 mgPOA
B24001Gyrase B240.1 mgPOA
B24005Gyrase B240.5 mgPOA
B24100Gyrase B241.0 mgPOA
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Drug-Resistant Topoisomerases

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We offer various quinolone- and coumarin-resistant topoisomerase mutants includingE.coliS.aureus and other organisms. The proteins can be supplied as separate subunits or as reconstituted enzyme. Typically the quinolone-resistant mutants confer 50-100 X more resistance to fluoroquinolones than the wild-type. We have more than 25 mutants in different topoisomerases and can make other mutants as requested. 

Technical Documents

Cat No.ProductPriceQuantity
AS83W001E.coli GyrASer83TrpPlease enquirePOA
AS83L001E.coli GyrASer83LeuPlease enquirePOA
BD426N001E.coli GyrBAsp426AsnPlease enquirePOA
SAAS84L01S.aureus GyrASer84LeuPlease enquirePOA
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inspiralis抗菌研究抗菌素耐药性是微生物(例如细菌,病毒和某些寄生虫)对抗菌药(例如抗生素和抗病毒剂)的作用产生耐药性的能力。我们的主要产品和服务领域之一是协助开发新的抗菌药物。拓扑异构酶:这些是抗菌化合物的重要目标。我们出售来自多种生物的拓扑异构酶和试剂盒。我们还提供筛选服务,以测试化合物的活性,确定作用机理或使用拓扑异构酶使化合物结晶。如果我们没有您需要的特定酶或突变体,我们可以为您制造。