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Cellscript™的使命是为临床研究和治疗提供最jia的产品和技术,用于制造和使用RNA在细胞中进行翻译。
目前的产品包括用于体外转录的试剂盒、使用cap模拟物或cap酶的5' RNA capping和3' RNA聚腺苷酸化的试剂盒,以及用于制造用于细胞翻译的cap、poly(a)-tail mRNA的all-in-one试剂盒。
Cellscript™最近推出了隐身™的体外合成RNA的RNA转录套件包含修饰核苷,如假尿苷(Ψ)和/或5-methylcytidine (m5C)代替相应的U或C规范核苷(图1)。这些工具都取名为“因为封顶,聚腺苷酸和核苷修饰的RNA产物(称为“INCOGNITO mRNAs”)是经过伪装的,因此当它们被转染到表达多种RNA传感器的哺乳动物细胞中时,不会像相应的未经修饰的mrna一样,引发先天免疫反应。
cellscript公司新设代理商
产品清单:
mRNA Production
T7 mScript™ Standard mRNA Production System (PDF)
| Simply the best way to make in vitro mRNA. Combines the benefits of high-yield transcription with those of post-transcriptional capping and tailing all in one kit. See T7-FlashScribe Transcription Kit, ScriptCap m7G Capping System, ScriptCap 2'-O-Methyltransferase Kit and A-Plus Poly(A) Polymerase Tailing Kit on this page. |
| C-MSC11610 | 10 reactions | $320 |
| C-MSC100625 | 25 reactions | $702 |
In Vitro Transcription
T7-FlashScribe™ Transcription Kit (PDF)
|
For the production of in vitro transcribed RNA with T7 RNA polymerase and canonical (GAUC) NTPs. A reaction produces 180 µg RNA from 1 µg DNA in 30 minutes. |
| C-ASF3507 | 50 reactions | $286 |
T7-Scribe™ Standard RNA IVT Kit (PDF)
| For the production of in vitro transcribed RNA with T7 RNA polymerase and canonical (GAUC) NTPs. A reaction produces 150 µg RNA from 1 µg DNA in 2 hours. |
| C-AS3107 | 50 reactions | $267 |
SP6-Scribe™ Standard RNA IVT Kit (PDF)
| For the production of in vitro transcribed RNA with SP6 RNA polymerase and canonical (GAUC) NTPs. A reaction produces 90 µg RNA from 1 µg DNA in 2 hours. |
| C-AS3106 | 50 reactions | $267 |
Post-Transcriptional Capping
ScriptCap™ m7G Capping System (PDF)
|
For post-transcriptional capping of in vitro transcribed RNA with ScriptCap Capping Enzyme, GTP and SAM. Cap 0 (N7-methyl-G) caps can be built with efficiencies approaching 100%. This cannot be accomplished with co-transcriptional capping methods. Use in conjunction with ScriptCap 2'-O-Methyltransferase to produce Cap 1 caps, that which is found on most eukaryotic mRNAs. |
| C-SCCE0625 | 25 reactions | $436 |
ScriptCap™ 2'-O-Methyltransferase Kit (PDF)
| For conversion of RNA containing Cap 0 caps to those containing Cap 1 caps, which are found on most eukaryotic mRNAs. Can be used simultaneously with ScriptCap m7G Capping System to produce virtually 100% Cap 1-capped RNA in a single reaction. |
| C-SCMT0625 | 25 reactions |
$219 |
| 图片/货号 | 产品名/品牌 | 价格/货期 | 操作 |
|---|---|---|---|
C-AS3106
|
Cellscript//SP6划线器™;标准RNA-IVT试剂盒/50反应/C-AS3106
Cellscript
|
¥3204.00 3-4周
|
我要询价 立即购买 |
C-ASF3507
|
Cellscript//T7 FlashScribe™;转录试剂盒/50反应/C-ASF3507
Cellscript
|
¥3432.00 3-4周
|
我要询价 立即购买 |
C-SCMT0625
|
Cellscript//ScriptCap™;2-O-甲基转移酶试剂盒/25反应/C-SCMT0625
Cellscript
|
¥2628.00 3-4周
|
我要询价 立即购买 |
C-ICTY110510
|
Cellscript/隐姓埋名™;T7和#936-RNA转录试剂盒/C-ICTY110510/10反应
Cellscript
|
¥4824.00 3-4周
|
我要询价 立即购买 |

