Bulk anti-CD62L In Vivo Antibody – Low Endotoxin (DREG56)
Bio X Cell:
ICH1017 is up to 11% cheaper for academia & non-profits and up to 51% cheaper for industry than the equivalent product CUS-HB-300 from Bio X Cell.We guarantee that our antibody will perform exactly the same in your experiments as CUS-HB-300 from Bio X Cell: if it doesn’t we will refund your purchase and pay for the Bio X Cell antibody to be delivered to you as soon as possible.
Product Benefits:
ichorbio’s anti-CD62L In Vivo Antibody – Low Endotoxin (DREG56) is manufactured in a cGMP compliant, ISO Quality Standard 9001:2015 facility. ichorbio’s low endotoxin antibodies have half the endotoxin of comparable antibodies from our competitors at less than 1.0 EU/mg. If ichorbio’s low endotoxin antibodies are not low enough we also offer ultra low endotoxin antibodies which have even less endotoxin (<0.75EU/mg) at an even higher purity (98% versus 95%). ichorbio offers Amazon vouchers or donations to the NC3Rs for reviews of this product: click here for more information. ichorbio: the best antibodies for in vivo research.
Target:
CD62L
Clone:
DREG56
Size:
ichorbio’s DREG56 in vivo antibody is available in the following bulk sizes:1mg, 5mg, 25mg, 50mg and 100mgichorbio regularly manufactures multi-gram amounts of our anti-CD62L DREG56 clone – please contact us for pricing.
Isotype:
Mouse IgG1
Other Names:
L-selectin, SELL, Leukocyte adhesion molecule 1, LAM-11Leukocyte surface antigen Leu-8, Leukocyte-endothelial cell adhesion molecule 1, LECAM1, Lymph node homing receptor1, TQ12, gp90-MEL, LNHR, LYAM1
Uniprot:
P14151
Host:
Mouse
Species Reactivity:
Human
Specificity:
Anti-CD62L In Vivo Antibody – Low Endotoxin (DREG56) recognizes an epitope on Human CD62L
Purification Method:
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Antigen Distribution:
Majority of B cells, naïve T cells, subset of memory T and NK cells, monocytes, granulocytes, thymocytes
Background:
L-selectin, also known as CD62L, is a cell adhesion molecule consisting of a large, highly glycosylated, extracellular domain found on leukocytes. It belongs to the selectin family of proteins, which recognise sialylated carbohydrate groups. L-selectin acts as a “homing receptor” for leukocytes to enter secondary lymphoid tissues via the high endothelial venules. L-selectin is an effective marker for separating lymphoid progenitors from myeloid progenitors and hematopoietic stem cells in bone marrow.
Concentration:
1.0 mg/ml
Formulation:
0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added. BSA and Azide free.
Purity:
>95% by SDS-PAGE and HPLC
>98% by SDS-PAGE and HPLC
Endotoxin:
≤ 1.0 EU/mg as determined by the LAL method
≤ 0.75 EU/mg as determined by the LAL method
Aggregation:
Aggregation level ≤ 5%
Aggregation level ≤ 1%
Storage:
anti-CD62L In Vivo Antibody – Low Endotoxin (DREG56) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
Applications:
Western Blot, Blocking, Functional Assays, Flow Cytometry
Application Notes:
Each investigator should determine their own optimal working dilution for specific applications.
Use:
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Isotype Control:
Mouse IgG1 Isotype Control for In Vivo – Low Endotoxin [HKSP] (ICH2247)
Antibodies against the same target:
Anti-CD62L In Vivo Antibody – Low Endotoxin [MEL-14] (ICH1060)
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