In vivo PolyMag™ Transfection Reagent has been designed for in vivo targeted transfection of various types of nucleic acids such as DNA, RNA, oligonucleotides using magnetic nanoparticles coated with specific polymers.  

DNA complexes can be easily administrated through various injection routes such as systemic administration (intravenous, intra-artery) or local administration (intratumoral, intracerebroventricular).

 

In vivo Magnetofection™ main advantages in comparison to other procedures:

• Increased transfection efficiency

• Targeted process (magnetically-driven)

• Reduction of the systemic dissemination of vectors during injection

• Reduction of the vector doses

• Work under non permissive conditions (hypothermia, physiological flow conditions)

• Penetration of the vector into tissues

• Minimized toxicity

• Universal – suitable for all nucleic acids

 

Sizes:

• 500 µL

• 1000 µL

 

Storage: +4°C

Shipping Conditions: Room temperature

 

• NB: This reagent needs to be used with a magnet

自2003年以来，OZ Biosciences为全球科学界和制药行业创建，开发和生产专门用于转染和转导工具的创新分子递送系统。OZ Biosciences专注于体外和体内应用的生物分子（例如DNA，RNA和蛋白质）的输送技术。在过去的几年中，生命科学经历了技术革命。在基因组学，功能基因组学和蛋白质组学领域所取得的进展为更好地理解基本生物学过程和开发下一代药物创造了绝佳的机会。