品牌分类
品牌咨询
联系方式
公司地址
苏州工业园区生物纳米园A4#216
联系电话
4000-520-616 / 18915418616
传真号码
0512-67156496
电子邮箱
info@ebiomall.com
公司网址
https://www.ebiomall.com
商品描述
BIOLOGICAL INFORMATION
DescriptionN-formyl-methionyl-leucyl-phenylalanine (fMLP), the chemotactic bacterial peptide, was able to specifically attenuate Ca2+ mobilization in human phagocytes induced by SAA, but only at very high concentrations. The bacterial peptide N-formyl-methionyl-leucyl-phenylalanine (fMLF) is one of the first identified and highly potent leukocyte chemoattractants. fMLF interacts with at least two human cell receptors formyl peptide receptor (FPR) and its variant formyl peptide receptor-like 1 (FPRL1), both are members of the seven transmembrane domain, G protein-coupled receptor (GPCR) family.
ApplicationMelanocortin
NoteFor research only, not for human use!
CHEMICAL INFORMATION
CAT No.ONP10601
CAS No.59880-97-6
NameN-Formyl-Met-Leu-Phe
Chemical NameN-Formyl-Met-Leu-Phe
Purity≥98%
SynonymsN/A
FormulaC21H31N3O5S
Molecular Weight437.56
One Letter CodeN-Formyl-MLF
Three Letter CodeN-Formyl-MET-LEU-PHE
SMILESCC(C)CC(C(=O)NC(CC1=CC=CC=C1)C(=O)O)NC(=O)C(CCSC)NC=O
InChI KeyPRQROPMIIGLWRP-BZSNNMDCSA-N
SourceSynthetic
FormDry Powder
ColorWhite
SolubilityN/A
SHIPPING & STORAGE
Storage4 degree ℃ for short term (weeks) and -20 degree ℃ for long term.
ShippingIce Pack
Stability≥ 2 years
REFERENCES & CITATIONS
1.Mills JSet al. Characterization of the binding site on the formyl peptide receptor using three receptor mutants and analogs of Met-Leu-Phe and Met-Met-Trp-Leu-Leu. J Biol Chem 275:39012-7 (2000). Read more (PubMed: 10960471)
2.Le Yet al. Novel pathophysiological role of classical chemotactic peptide receptors and their communications with chemokine receptors. Immunol Rev 177:185-94 (2000). Read more (PubMed: 11138775)
3.Katada Tet al. Synergistic activation of a family of phosphoinositide 3-kinase via G-protein coupled and tyrosine kinase-related receptors. Chem Phys Lipids 98:79-86 (1999). Read more (PubMed: 10358930)
DOCUMENTATIONS
- COA
- Data sheet
- MS
- RP-HPLC
- MSDS
- Handling Instruction
PROMOTIONS & EVENTS
