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商品描述
BIOLOGICAL INFORMATION
DescriptionThe C-peptide of proinsulin is important for the biosynthesis of insulin but has for a long time been considered to be biologically inert. Data now indicates that C-peptide administration is accompanied by augmented blood flow in skeletal muscle and skin, diminished glomerular hyperfiltration, reduced urinary albumin excretion, and improved nerve function. The possibility exists that C-peptide replacement, together with insulin administration, may prevent the development or retard the progression of long-term complications in type 1 diabetes.
ApplicationMelanocortin
NoteFor research only, not for human use!
CHEMICAL INFORMATION
CAT No.ONP10137
CAS No.39016-05-2
NameC-Peptide, dog
Chemical NameC-Peptide,-dog
Purity≥98%
SynonymsN/A
FormulaC137H225N37O49
Molecular Weight3174.49
One Letter CodeEVEDLQVRDVELAGAPGEGGLQPLALEGALQ
Three Letter CodeGLU-VAL-GLU-ASP-LEU-GLN-VAL-ARG-ASP-VAL-GLU-LEU-ALA-GLY-ALA-PRO-GLY-GLU-GLY-GLY-LEU-GLN-PRO-LEU-ALA-LEU-GLU-GLY-ALA-LEU-GLN
SMILESCC(C)CC(C(=O)NC(CCC(=O)N)C(=O)N1CCCC1C(=O)NC(CC(C)C)C(=O)NC(C)C(=O)NC(CC(C)C)C(=O)NC(CCC(=O)O)C(=O)NCC(=O)NC(C)C(=O)NC(CC(C)C)C(=O)NC(CCC(=O)N)C(=O)O)NC(=O)CNC(=O)CNC(=O)C(CCC(=O)O)NC(=O)CNC(=O)C2CCCN2C(=O)C(C)NC(=O)CNC(=O)C(C)NC(=O)C(CC(C)C)NC(=O)C(CCC(=O)O)NC(=O)C(C(C)C)NC(=O)C(CC(=O)O)NC(=O)C(CCCNC(=N)N)NC(=O)C(C(C)C)NC(=O)C(CCC(=O)N)NC(=O)C(CC(C)C)NC(=O)C(CC(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C(C(C)C)NC(=O)C(CCC(=O)O)N
InChI KeyYNYDBXCGKFIALM-LXWAIWELSA-N
SourceSynthetic
FormDry Powder
ColorWhite
SolubilityN/A
SHIPPING & STORAGE
Storage4 degree ℃ for short term (weeks) and -20 degree ℃ for long term.
ShippingBlue Ice
Stability≥ 2 years
REFERENCES & CITATIONS
1.Hills CE, Brunskill NJ. Intracellular signalling by C-peptide. Exp Diabetes Res. 2008;2008:635158. PMID: 18382618.
2.Samnegård B, Jacobson SH, Jaremko G, et al. Effects of C-peptide on glomerular and renal size and renal function in diabetic rats. Kidney Int. 2001 Oct;60(4):1258-65. PMID: 11576340.
3.Sima AA, Zhang W, Sugimoto K, et al. C-peptide prevents and improves chronic Type I diabetic polyneuropathy in the BB/Wor rat. Diabetologia. 2001 Jul;44(7):889-97. PMID: 11508275.
DOCUMENTATIONS
- COA
- Data sheet
- MS
- RP-HPLC
- MSDS
- Handling Instruction
PROMOTIONS & EVENTS
