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商品描述
BIOLOGICAL INFORMATION
DescriptionIt has been demonstrated that the RGD-containing peptide, c(GRGDSPA), inhibited the binding of fibronectin to stimulated platelets with IC₅₀= 0.223 µM. c(GRGDSPA) also blocked thrombin-induced platelet aggregation with IC₅₀= 32 µM, but was less potent than native fibronectin in this respect.
ApplicationMelanocortin
NoteFor research only, not for human use!
CHEMICAL INFORMATION
CAT No.ONP10940
CAS No.128857-77-2
NameCyclo(Gly-Arg-Gly-Asp-Ser-Pro-Ala)
Chemical NameCyclo(Gly-Arg-Gly-Asp-Ser-Pro-Ala)
Purity≥98%
Synonymscyclic GRGDSPA
FormulaC25H40N10O10
Molecular Weight640.65
One Letter CodeN/A
Three Letter CodeCyclo(Gly-Arg-Gly-Asp-Ser-Pro-Ala)
SMILESCC1C(=O)NCC(=O)NC(C(=O)NCC(=O)NC(C(=O)NC(C(=O)N2CCCC2C(=O)N1)CO)CC(=O)O)CCCN=C(N)N
InChI KeyFWFZEPRYKXWBLR-QXKUPLGCSA-N
SourceSynthetic
FormDry Powder
ColorWhite
SolubilityN/A
SHIPPING & STORAGE
Storage4 degree ℃ for short term (weeks) and -20 degree ℃ for long term.
ShippingBlue Ice
Stability≥ 2 years
REFERENCES & CITATIONS
1.S.S.Huang et al., FEBS Lett., 565, 117 (2004)
2.W.C.Wildering et al., J. Neurosci., 22, 2419 (2002)
3.M.Ayaki et al., Biochim. Biophys. Acta, 1495, 40 (2000)
DOCUMENTATIONS
- COA
- Data sheet
- MS
- RP-HPLC
- MSDS
- Handling Instruction
PROMOTIONS & EVENTS
