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商品描述
BIOLOGICAL INFORMATION
DescriptionFMRF-amide belongs to Molluscan Cardioexcitatory Neuropeptide. This peptide appears to localize with neuropeptide Y in some regions of the brain. FMRF-amide inhibits Na+-Ca2+ exchange in cardiac sarcolemma vesicles. The neuropeptide FMRF-amide stimulated enzyme activity 7- to 8-fold (EC50, 1 mM) via receptors that were pharmacologically distinct from those for dopamine and serotonin. FMRF- amide augmented cyclic AMP levels in slices of gill tissue with a time course similar to that for adenylate cyclase activation.
ApplicationMelanocortin
NoteFor research only, not for human use!
CHEMICAL INFORMATION
CAT No.ONP10050
CAS No.64190-70-1
NamePhe-Met-Arg-Phe
Chemical NamePhe-Met-Arg-Phe
Purity≥98%
SynonymsF-M-R-F;-amide; Phe-Met-Arg-Phe amideMolluscan cardioexcitatory neuropeptide
FormulaC29H42N8O4S1
Molecular Weight599.8
One Letter CodeFMRF
Three Letter CodePHE-MET-ARG-PHE
SMILESCSCCC(C(=O)NC(CCCN=C(N)N)C(=O)NC(CC1=CC=CC=C1)C(=O)N)NC(=O)C(CC2=CC=CC=C2)N
InChI KeyWCSPDMCSKYUFBX-UHFFFAOYSA-N
SourceSynthetic
FormDry Powder
ColorWhite
SolubilityN/A
SHIPPING & STORAGE
Storage4 degree ℃ for short term (weeks) and -20 degree ℃ for long term.
ShippingBlue Ice
Stability≥ 2 years
REFERENCES & CITATIONS
1.Twan WH, et al. The presence and ancestral role of gonadotropin-releasing hormone in the reproduction of scleractinian coral, Euphyllia ancora. Endocrinology. Jan 2006; 147(1): 397-406.
2.Yamanaka N, et al. Identification of a novel prothoracicostatic hormone and its receptor in the silkworm Bombyx mori.J Biol Chem. Apr 2005; 280(15): 14684-14690.
3.P.Marciniak and G.Rosinski, Invertebrate Reproduction & Development, 54, 1 (2010)
DOCUMENTATIONS
- COA
- Data sheet
- MS
- RP-HPLC
- MSDS
- Handling Instruction
PROMOTIONS & EVENTS
